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Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers.

Thum T, Erpenbeck VJ, Moeller J, Hohlfeld JM, Krug N, Borlak J.

Environ Health Perspect. 2006 Nov;114(11):1655-61.PMID: 17107849 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers.

Willey JC, Coy EL, Frampton MW, Torres A, Apostolakos MJ, Hoehn G, Schuermann WH, Thilly WG, Olson DE, Hammersley JR, Crespi CL, Utell MJ.

Am J Respir Cell Mol Biol. 1997 Jul;17(1):114-24.PMID: 9224217 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers.

Piipari R, Savela K, Nurminen T, Hukkanen J, Raunio H, Hakkola J, Mäntylä T, Beaune P, Edwards RJ, Boobis AR, Anttila S.

Int J Cancer. 2000 Jun 1;86(5):610-6.PMID: 10797280 [PubMed - indexed for MEDLINE]Related articles

Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S.

Mol Pharmacol. 2006 Jul;70(1):329-39. Epub 2006 Apr 11.PMID: 16608920 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis.

Oyama T, Sugio K, Uramoto H, Iwata T, Onitsuka T, Isse T, Nozoe T, Kagawa N, Yasumoto K, Kawamoto T.

Front Biosci. 2007 May 1;12:4497-503.PMID: 17485391 [PubMed - indexed for MEDLINE]Related articles

Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung.

Hukkanen J, Pelkonen O, Hakkola J, Raunio H.

Crit Rev Toxicol. 2002 Sep;32(5):391-411. Review.PMID: 12389869 [PubMed - indexed for MEDLINE]Related articles

Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues.

Macé K, Bowman ED, Vautravers P, Shields PG, Harris CC, Pfeifer AM.

Eur J Cancer. 1998 May;34(6):914-20.PMID: 9797707 [PubMed - indexed for MEDLINE]Related articles

Methylation of cytochrome P4501A1 promoter in the lung is associated with tobacco smoking.

Anttila S, Hakkola J, Tuominen P, Elovaara E, Husgafvel-Pursiainen K, Karjalainen A, Hirvonen A, Nurminen T.

Cancer Res. 2003 Dec 15;63(24):8623-8.PMID: 14695173 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach.

Castell JV, Donato MT, Gómez-Lechón MJ.

Exp Toxicol Pathol. 2005 Jul;57 Suppl 1:189-204. Review.PMID: 16092727 [PubMed - indexed for MEDLINE]Related articles

The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

Pascussi JM, Gerbal-Chaloin S, Drocourt L, Maurel P, Vilarem MJ.

Biochim Biophys Acta. 2003 Feb 17;1619(3):243-53. Review.PMID: 12573484 [PubMed - indexed for MEDLINE]Related articles

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents.

Mani S, Huang H, Sundarababu S, Liu W, Kalpana G, Smith AB, Horwitz SB.

Clin Cancer Res. 2005 Sep 1;11(17):6359-69.PMID: 16144941 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.

Endo K, Uno S, Seki T, Ariga T, Kusumi Y, Mitsumata M, Yamada S, Makishima M.

Toxicol Appl Pharmacol. 2008 Jul 15;230(2):135-43. Epub 2008 Feb 21.PMID: 18372000 [PubMed - indexed for MEDLINE]Related articles

Transcript profiling of cytochrome P450 genes in HL-60 human leukemic cells: upregulation of CYP1B1 by all-trans-retinoic acid.

Kawai M, Chen J, Cheung CY, Chang TK.

Mol Cell Biochem. 2003 Jun;248(1-2):57-65.PMID: 12870655 [PubMed - indexed for MEDLINE]Related articles

Transcriptional profiling of genes induced in the livers of patients treated with carbamazepine.

Oscarson M, Zanger UM, Rifki OF, Klein K, Eichelbaum M, Meyer UA.

Clin Pharmacol Ther. 2006 Nov;80(5):440-456.PMID: 17112801 [PubMed - indexed for MEDLINE]Related articles

Differential modulation of leukotriene B4 synthesis and degradation in human bronchoalveolar lavage cells by lipopolysaccharide and tobacco smoke.

Mao JT, Tashkin DP, Tsu IH, Serio KJ.

Cancer Prev Res (Phila Pa). 2008 Sep;1(4):266-74.PMID: 19138970 [PubMed - indexed for MEDLINE]Related articles

Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers.

Kim JH, Sherman ME, Curriero FC, Guengerich FP, Strickland PT, Sutter TR.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):210-9.PMID: 15364538 [PubMed - indexed for MEDLINE]Related articles

Human cytochrome p450 2s1: lack of activity in the metabolic activation of several cigarette smoke carcinogens and in the metabolism of nicotine.

Wang SL, He XY, Hong JY.

Drug Metab Dispos. 2005 Mar;33(3):336-40. Epub 2004 Dec 17.PMID: 15608128 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor.

Kakizaki S, Yamazaki Y, Kosone T, Horiguchi N, Sohara N, Sato K, Takagi H, Yoshinari K, Mori M.

Liver Int. 2007 Feb;27(1):109-19. Erratum in: Liver Int. 2007 Jun;27(5):733. Horigichi, Norio [corrected to Horiguchi, Norio]. PMID: 17241389 [PubMed - indexed for MEDLINE]Related articles

Xenobiotic-metabolizing enzymes in human lung.

Zhang JY, Wang Y, Prakash C.

Curr Drug Metab. 2006 Dec;7(8):939-48. Review.PMID: 17168693 [PubMed - indexed for MEDLINE]Related articles

Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas.

Chang JT, Chang H, Chen PH, Lin SL, Lin P.

Clin Cancer Res. 2007 Jan 1;13(1):38-45.PMID: 17200336 [PubMed - indexed for MEDLINE]Related articlesFree article