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PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract.

Ma R, Sassoon DA.

Environ Health Perspect. 2006 Jun;114(6):898-904.PMID: 16759992 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt7a is a suppressor of cell death in the female reproductive tract and is required for postnatal and estrogen-mediated growth.

Carta L, Sassoon D.

Biol Reprod. 2004 Aug;71(2):444-54. Epub 2004 Apr 7.PMID: 15070830 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract.

Couse JF, Dixon D, Yates M, Moore AB, Ma L, Maas R, Korach KS.

Dev Biol. 2001 Oct 15;238(2):224-38.PMID: 11784006 [PubMed - indexed for MEDLINE]Related articles

Diethylstilbestrol exposure in utero: a paradigm for mechanisms leading to adult disease.

Mericskay M, Carta L, Sassoon D.

Birth Defects Res A Clin Mol Teratol. 2005 Mar;73(3):133-5.PMID: 15751030 [PubMed - indexed for MEDLINE]Related articles

Wnt genes and endocrine disruption of the female reproductive tract: a genetic approach.

Sassoon D.

Mol Cell Endocrinol. 1999 Dec 20;158(1-2):1-5. Review.PMID: 10630399 [PubMed - indexed for MEDLINE]Related articles

Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations.

Newbold RR, Padilla-Banks E, Jefferson WN.

Endocrinology. 2006 Jun;147(6 Suppl):S11-7. Epub 2006 May 11. Review.PMID: 16690809 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term effects of neonatal exposure to hydroxylated polychlorinated biphenyls in the BALB/cCrgl mouse.

Martinez JM, Stephens LC, Jones LA.

Environ Health Perspect. 2005 Aug;113(8):1022-6.PMID: 16079073 [PubMed - indexed for MEDLINE]Related articlesFree article

Lessons learned from perinatal exposure to diethylstilbestrol.

Newbold RR.

Toxicol Appl Pharmacol. 2004 Sep 1;199(2):142-50. Review.PMID: 15313586 [PubMed - indexed for MEDLINE]Related articles

Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells.

Carmon KS, Loose DS.

Mol Cancer Res. 2008 Jun;6(6):1017-28.PMID: 18567805 [PubMed - indexed for MEDLINE]Related articlesFree article

Biochemical and molecular changes at the cellular level in response to exposure to environmental estrogen-like chemicals.

Roy D, Palangat M, Chen CW, Thomas RD, Colerangle J, Atkinson A, Yan ZJ.

J Toxicol Environ Health. 1997 Jan;50(1):1-29. Review.PMID: 9015129 [PubMed - indexed for MEDLINE]Related articles

Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract.

Couse JF, Korach KS.

Toxicology. 2004 Dec 1;205(1-2):55-63. Review.PMID: 15458790 [PubMed - indexed for MEDLINE]Related articles

Estrogens modulate the gene expression of Wnt-7a in cultured endometrial adenocarcinoma cells.

Wagner J, Lehmann L.

Mol Nutr Food Res. 2006 Apr;50(4-5):368-72.PMID: 16534752 [PubMed - indexed for MEDLINE]Related articles

Developmental diethylstilbestrol exposure alters genetic pathways of uterine cytodifferentiation.

Huang WW, Yin Y, Bi Q, Chiang TC, Garner N, Vuoristo J, McLachlan JA, Ma L.

Mol Endocrinol. 2005 Mar;19(3):669-82. Epub 2004 Dec 9.PMID: 15591538 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased expression of Wnt7a mRNA is inversely associated with the expression of estrogen receptor-alpha in human uterine leiomyoma.

Li S, Chiang TC, Davis GR, Williams RM, Wilson VP, McLachlan JA.

J Clin Endocrinol Metab. 2001 Jan;86(1):454-7.PMID: 11232041 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus.

Li S, Hansman R, Newbold R, Davis B, McLachlan JA, Barrett JC.

Mol Carcinog. 2003 Oct;38(2):78-84.PMID: 14502647 [PubMed - indexed for MEDLINE]Related articles

Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.

Dickerson SM, Gore AC.

Rev Endocr Metab Disord. 2007 Jun;8(2):143-59. Review.PMID: 17674209 [PubMed - indexed for MEDLINE]Related articles

Differential activation of the calcium/protein kinase C and the canonical beta-catenin pathway by Wnt1 and Wnt7a produces opposite effects on cell proliferation in PC12 cells.

Spinsanti P, De Vita T, Caruso A, Melchiorri D, Misasi R, Caricasole A, Nicoletti F.

J Neurochem. 2008 Mar;104(6):1588-98. Epub 2007 Nov 5.PMID: 17988238 [PubMed - indexed for MEDLINE]Related articles

[Endocrine disruptor compounds and their role in the developmental programming of the reproductive axis]

Guzmán C, Zambrano E.

Rev Invest Clin. 2007 Jan-Feb;59(1):73-81. Review. Spanish. PMID: 17569302 [PubMed - indexed for MEDLINE]Related articles

Environmental estrogens and reproductive health: a discussion of the human and environmental data.

Daston GP, Gooch JW, Breslin WJ, Shuey DL, Nikiforov AI, Fico TA, Gorsuch JW.

Reprod Toxicol. 1997 Jul-Aug;11(4):465-81. Review.PMID: 9241667 [PubMed - indexed for MEDLINE]Related articles

Environmental endocrine modulators and human health: an assessment of the biological evidence.

Golden RJ, Noller KL, Titus-Ernstoff L, Kaufman RH, Mittendorf R, Stillman R, Reese EA.

Crit Rev Toxicol. 1998 Mar;28(2):109-227. Review.PMID: 9557209 [PubMed - indexed for MEDLINE]Related articles