PubMed

Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolites.

Su PF, Hu YJ, Ho IC, Cheng YM, Lee TC.

Environ Health Perspect. 2006 Mar;114(3):394-403.PMID: 16507463 [PubMed - indexed for MEDLINE]Related articlesFree article

Arsenite and its mono- and dimethylated trivalent metabolites enhance the formation of benzo[a]pyrene diol epoxide-DNA adducts in Xeroderma pigmentosum complementation group A cells.

Shen S, Lee J, Cullen WR, Le XC, Weinfeld M.

Chem Res Toxicol. 2009 Feb;22(2):382-90.PMID: 19146383 [PubMed - indexed for MEDLINE]Related articles

Expression of AS3MT alters transcriptional profiles in human urothelial cells exposed to arsenite.

Hester S, Drobná Z, Andrews D, Liu J, Waalkes M, Thomas Dj, Styblo M.

Hum Exp Toxicol. 2009 Jan;28(1):49-61.PMID: 19411561 [PubMed - indexed for MEDLINE]Related articles

Oxidation and methylation status determine the effects of arsenic on the mitotic apparatus.

Kligerman AD, Doerr CL, Tennant AH.

Mol Cell Biochem. 2005 Nov;279(1-2):113-21.PMID: 16283520 [PubMed - indexed for MEDLINE]Related articles

Arsenite and its metabolites, MMA(III) and DMA(III), modify CYP3A4, PXR and RXR alpha expression in the small intestine of CYP3A4 transgenic mice.

Medina-Díaz IM, Estrada-Muñiz E, Reyes-Hernández OD, Ramírez P, Vega L, Elizondo G.

Toxicol Appl Pharmacol. 2009 Sep 1;239(2):162-8. Epub 2008 Nov 24.PMID: 19084030 [PubMed - indexed for MEDLINE]Related articles

Trivalent arsenicals induce lipid peroxidation, protein carbonylation, and oxidative DNA damage in human urothelial cells.

Wang TC, Jan KY, Wang AS, Gurr JR.

Mutat Res. 2007 Feb 3;615(1-2):75-86. Epub 2006 Nov 28.PMID: 17134727 [PubMed - indexed for MEDLINE]Related articles

Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice.

Xie Y, Trouba KJ, Liu J, Waalkes MP, Germolec DR.

Environ Health Perspect. 2004 Aug;112(12):1255-63.PMID: 15345372 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro.

Nascimento MG, Suzuki S, Wei M, Tiwari A, Arnold LL, Lu X, Le XC, Cohen SM.

Toxicology. 2008 Jul 10;249(1):69-74. Epub 2008 Apr 22.PMID: 18502017 [PubMed - indexed for MEDLINE]Related articles

Monomethylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes.

Petrick JS, Ayala-Fierro F, Cullen WR, Carter DE, Vasken Aposhian H.

Toxicol Appl Pharmacol. 2000 Mar 1;163(2):203-7.PMID: 10698679 [PubMed - indexed for MEDLINE]Related articles

DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species.

Nesnow S, Roop BC, Lambert G, Kadiiska M, Mason RP, Cullen WR, Mass MJ.

Chem Res Toxicol. 2002 Dec;15(12):1627-34.PMID: 12482246 [PubMed - indexed for MEDLINE]Related articles

Toxicity of dimethylmonothioarsinic acid toward human epidermoid carcinoma A431 cells.

Naranmandura H, Ibata K, Suzuki KT.

Chem Res Toxicol. 2007 Aug;20(8):1120-5. Epub 2007 Jul 13.PMID: 17630711 [PubMed - indexed for MEDLINE]Related articles

Uptake of inorganic and organic derivatives of arsenic associated with induced cytotoxic and genotoxic effects in Chinese hamster ovary (CHO) cells.

Dopp E, Hartmann LM, Florea AM, von Recklinghausen U, Pieper R, Shokouhi B, Rettenmeier AW, Hirner AV, Obe G.

Toxicol Appl Pharmacol. 2004 Dec 1;201(2):156-65.PMID: 15541755 [PubMed - indexed for MEDLINE]Related articles

Forced uptake of trivalent and pentavalent methylated and inorganic arsenic and its cyto-/genotoxicity in fibroblasts and hepatoma cells.

Dopp E, Hartmann LM, von Recklinghausen U, Florea AM, Rabieh S, Zimmermann U, Shokouhi B, Yadav S, Hirner AV, Rettenmeier AW.

Toxicol Sci. 2005 Sep;87(1):46-56. Epub 2005 Jun 9.PMID: 15947026 [PubMed - indexed for MEDLINE]Related articlesFree article

Further evidence against a direct genotoxic mode of action for arsenic-induced cancer.

Klein CB, Leszczynska J, Hickey C, Rossman TG.

Toxicol Appl Pharmacol. 2007 Aug 1;222(3):289-97. Epub 2007 Jan 8.PMID: 17316729 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxicity of inorganic arsenic and its metabolites on haematopoietic progenitors "in vitro": comparison between species and sexes.

Ferrario D, Croera C, Brustio R, Collotta A, Bowe G, Vahter M, Gribaldo L.

Toxicology. 2008 Jul 30;249(2-3):102-8. Epub 2008 Apr 22.PMID: 18524450 [PubMed - indexed for MEDLINE]Related articles

Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture.

Eblin KE, Bowen ME, Cromey DW, Bredfeldt TG, Mash EA, Lau SS, Gandolfi AJ.

Toxicol Appl Pharmacol. 2006 Nov 15;217(1):7-14. Epub 2006 Jul 21.PMID: 16930658 [PubMed - indexed for MEDLINE]Related articles

Role of the alkali labile sites, reactive oxygen species and antioxidants in DNA damage induced by methylated trivalent metabolites of inorganic arsenic.

Soto-Reyes E, Del Razo LM, Valverde M, Rojas E.

Biometals. 2005 Oct;18(5):493-506.PMID: 16333750 [PubMed - indexed for MEDLINE]Related articles

Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes.

Vega L, Styblo M, Patterson R, Cullen W, Wang C, Germolec D.

Toxicol Appl Pharmacol. 2001 May 1;172(3):225-32.PMID: 11312651 [PubMed - indexed for MEDLINE]Related articles

Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Chen B, Le XC, Cohen SM.

Toxicol Lett. 2009 Jun 1;187(2):124-9. Epub 2009 Mar 3.PMID: 19429254 [PubMed - indexed for MEDLINE]Related articles

The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds.

Hirano S, Kobayashi Y, Cui X, Kanno S, Hayakawa T, Shraim A.

Toxicol Appl Pharmacol. 2004 Aug 1;198(3):458-67. Review.PMID: 15276427 [PubMed - indexed for MEDLINE]Related articles