PubMed

The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance.

Alonso-Magdalena P, Morimoto S, Ripoll C, Fuentes E, Nadal A.

Environ Health Perspect. 2006 Jan;114(1):106-12.PMID: 16393666 [PubMed - indexed for MEDLINE]Related articlesFree article

Bisphenol-A disruption of the endocrine pancreas and blood glucose homeostasis.

Ropero AB, Alonso-Magdalena P, García-García E, Ripoll C, Fuentes E, Nadal A.

Int J Androl. 2008 Apr;31(2):194-200. Epub 2007 Oct 31. Review.PMID: 17971160 [PubMed - indexed for MEDLINE]Related articles

The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes.

Nadal A, Alonso-Magdalena P, Soriano S, Quesada I, Ropero AB.

Mol Cell Endocrinol. 2009 May 25;304(1-2):63-8. Epub 2009 Mar 9. Review.PMID: 19433249 [PubMed - indexed for MEDLINE]Related articles

Pancreatic insulin content regulation by the estrogen receptor ER alpha.

Alonso-Magdalena P, Ropero AB, Carrera MP, Cederroth CR, Baquié M, Gauthier BR, Nef S, Stefani E, Nadal A.

PLoS One. 2008 Apr 30;3(4):e2069.PMID: 18446233 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia.

Garris DR, Garris BL.

Cell Tissue Res. 2005 Feb;319(2):231-42. Epub 2004 Nov 20.PMID: 15654653 [PubMed - indexed for MEDLINE]Related articles

Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.

Alonso-Magdalena P, Laribi O, Ropero AB, Fuentes E, Ripoll C, Soria B, Nadal A.

Environ Health Perspect. 2005 Aug;113(8):969-77.PMID: 16079065 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoting insulin secretion in pancreatic islets by means of bisphenol A and nonylphenol via intracellular estrogen receptors.

Adachi T, Yasuda K, Mori C, Yoshinaga M, Aoki N, Tsujimoto G, Tsuda K.

Food Chem Toxicol. 2005 May;43(5):713-9.PMID: 15778011 [PubMed - indexed for MEDLINE]Related articles

Effects of sub-chronic exposure to naturally occurring N-terminally truncated metabolites of glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), GIP(3-42) and GLP-1(9-36)amide, on insulin secretion and glucose homeostasis in ob/ob mice.

Parker JC, Lavery KS, Irwin N, Green BD, Greer B, Harriott P, O'Harte FP, Gault VA, Flatt PR.

J Endocrinol. 2006 Oct;191(1):93-100.PMID: 17065392 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent expansion of pancreatic beta-cells by the protein p8 in vitro and in vivo.

Päth G, Opel A, Gehlen M, Rothhammer V, Niu X, Limbert C, Romfeld L, Hügl S, Knoll A, Brendel MD, Bretzel RG, Seufert J.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1168-76. Epub 2006 Jul 5.PMID: 16822955 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel glucagon-like peptide-1 (GLP-1) analog (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta-cell function after 3-week daily administration in obese diabetic (ob/ob) mice.

Green BD, Lavery KS, Irwin N, O'harte FP, Harriott P, Greer B, Bailey CJ, Flatt PR.

J Pharmacol Exp Ther. 2006 Aug;318(2):914-21. Epub 2006 Apr 28.PMID: 16648370 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin plus low-dose glimeperide significantly improves Homeostasis Model Assessment for insulin resistance (HOMA(IR)) and beta-cell function (HOMA(beta-cell)) without hyperinsulinemia in patients with type 2 diabetes mellitus.

Bermúdez-Pirela VJ, Cano C, Medina MT, Souki A, Lemus MA, Leal EM, Seyfi HA, Cano R, Ciscek A, Bermúdez-Arias F, Contreras F, Israili ZH, Hernández-Hernández R, Valasco M.

Am J Ther. 2007 Mar-Apr;14(2):194-202.PMID: 17414590 [PubMed - indexed for MEDLINE]Related articles

Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure.

Welshons WV, Nagel SC, vom Saal FS.

Endocrinology. 2006 Jun;147(6 Suppl):S56-69. Epub 2006 May 11. Review.PMID: 16690810 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin regulates insulin release and glycemia: physiological role and therapeutic potential.

Yada T, Dezaki K, Sone H, Koizumi M, Damdindorj B, Nakata M, Kakei M.

Curr Diabetes Rev. 2008 Feb;4(1):18-23. Review.PMID: 18220691 [PubMed - indexed for MEDLINE]Related articles

Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.

Picard F, Wanatabe M, Schoonjans K, Lydon J, O'Malley BW, Auwerx J.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15644-8. Epub 2002 Nov 15.PMID: 12438645 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.

Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, Lin-Shiau SY, Liu SH.

Diabetes. 2006 Jun;55(6):1614-24.PMID: 16731823 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice.

Savontaus E, Fagerholm V, Rahkonen O, Scheinin M.

Eur J Pharmacol. 2008 Jan 14;578(2-3):359-64. Epub 2007 Oct 2.PMID: 17964569 [PubMed - indexed for MEDLINE]Related articles

An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment.

vom Saal FS, Hughes C.

Environ Health Perspect. 2005 Aug;113(8):926-33. Review.PMID: 16079060 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats.

Choi SB, Jang JS, Park S.

Endocrinology. 2005 Nov;146(11):4786-94. Epub 2005 Jul 21.PMID: 16037383 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetes.

Jackerott M, Møldrup A, Thams P, Galsgaard ED, Knudsen J, Lee YC, Nielsen JH.

Diabetes. 2006 Oct;55(10):2705-12.PMID: 17003334 [PubMed - indexed for MEDLINE]Related articlesFree article

GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice.

Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA.

Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E157-67. Epub 2007 Oct 30.PMID: 17971510 [PubMed - indexed for MEDLINE]Related articlesFree article