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    Results: 1 to 20 of 155

    1.

    Ascorbate depletion: a critical step in nickel carcinogenesis?

    Salnikow K, Kasprzak KS.

    Environ Health Perspect. 2005 May;113(5):577-84. Review.PMID: 15866766 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.

    Karaczyn A, Ivanov S, Reynolds M, Zhitkovich A, Kasprzak KS, Salnikow K.

    J Cell Biochem. 2006 Apr 1;97(5):1025-35.PMID: 16288478 [PubMed - indexed for MEDLINE]Related articles

    3.

    The role of ascorbate in the modulation of HIF-1alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II).

    Kaczmarek M, Timofeeva OA, Karaczyn A, Malyguine A, Kasprzak KS, Salnikow K.

    Free Radic Biol Med. 2007 Apr 15;42(8):1246-57. Epub 2007 Jan 19.PMID: 17382205 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.

    Pagé EL, Chan DA, Giaccia AJ, Levine M, Richard DE.

    Mol Biol Cell. 2008 Jan;19(1):86-94. Epub 2007 Oct 17.PMID: 17942596 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Nickel carcinogenesis.

    Kasprzak KS, Sunderman FW Jr, Salnikow K.

    Mutat Res. 2003 Dec 10;533(1-2):67-97. Review.PMID: 14643413 [PubMed - indexed for MEDLINE]Related articles

    6.

    Soluble nickel interferes with cellular iron homeostasis.

    Davidson T, Chen H, Garrick MD, D'Angelo G, Costa M.

    Mol Cell Biochem. 2005 Nov;279(1-2):157-62.PMID: 16283525 [PubMed - indexed for MEDLINE]Related articles

    7.

    Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes.

    Li Q, Chen H, Huang X, Costa M.

    Toxicol Appl Pharmacol. 2006 Jun 15;213(3):245-55. Epub 2006 Jan 4.PMID: 16386771 [PubMed - indexed for MEDLINE]Related articles

    8.

    Nickel carcinogenesis: epigenetics and hypoxia signaling.

    Costa M, Davidson TL, Chen H, Ke Q, Zhang P, Yan Y, Huang C, Kluz T.

    Mutat Res. 2005 Dec 30;592(1-2):79-88. Epub 2005 Jul 11. Review.PMID: 16009382 [PubMed - indexed for MEDLINE]Related articles

    9.

    Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.

    Elmore AR.

    Int J Toxicol. 2005;24 Suppl 2:51-111. Review.PMID: 16154915 [PubMed - indexed for MEDLINE]Related articles

    10.

    Respiratory carcinogenicity assessment of soluble nickel compounds.

    Oller AR.

    Environ Health Perspect. 2002 Oct;110 Suppl 5:841-4. Review.PMID: 12426143 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Free radicals, metals and antioxidants in oxidative stress-induced cancer.

    Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M.

    Chem Biol Interact. 2006 Mar 10;160(1):1-40. Epub 2006 Jan 23. Review.PMID: 16430879 [PubMed - indexed for MEDLINE]Related articles

    12.

    Metals, toxicity and oxidative stress.

    Valko M, Morris H, Cronin MT.

    Curr Med Chem. 2005;12(10):1161-208. Review.PMID: 15892631 [PubMed - indexed for MEDLINE]Related articles

    13.

    Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate.

    Vissers MC, Gunningham SP, Morrison MJ, Dachs GU, Currie MJ.

    Free Radic Biol Med. 2007 Mar 15;42(6):765-72. Epub 2006 Nov 30.PMID: 17320759 [PubMed - indexed for MEDLINE]Related articles

    14.

    Soluble nickel inhibits HIF-prolyl-hydroxylases creating persistent hypoxic signaling in A549 cells.

    Davidson TL, Chen H, Di Toro DM, D'Angelo G, Costa M.

    Mol Carcinog. 2006 Jul;45(7):479-89.PMID: 16649251 [PubMed - indexed for MEDLINE]Related articles

    15.

    Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate.

    Jones DT, Trowbridge IS, Harris AL.

    Cancer Res. 2006 Mar 1;66(5):2749-56.PMID: 16510596 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.

    Chan DA, Sutphin PD, Yen SE, Giaccia AJ.

    Mol Cell Biol. 2005 Aug;25(15):6415-26.PMID: 16024780 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells.

    Chen H, Davidson T, Singleton S, Garrick MD, Costa M.

    Toxicol Appl Pharmacol. 2005 Aug 15;206(3):275-87. Epub 2004 Dec 25.PMID: 16039939 [PubMed - indexed for MEDLINE]Related articles

    18.

    Effect of metal ions on HIF-1alpha and Fe homeostasis in human A549 cells.

    Kang GS, Li Q, Chen H, Costa M.

    Mutat Res. 2006 Nov 7;610(1-2):48-55. Epub 2006 Jul 31.PMID: 16877034 [PubMed - indexed for MEDLINE]Related articles

    19.

    Carcinogenic effect of nickel compounds.

    Lu H, Shi X, Costa M, Huang C.

    Mol Cell Biochem. 2005 Nov;279(1-2):45-67. Review.PMID: 16283514 [PubMed - indexed for MEDLINE]Related articles

    20.

    Risk assessment of nickel carcinogenicity and occupational lung cancer.

    Shen HM, Zhang QF.

    Environ Health Perspect. 1994 Jan;102 Suppl 1:275-82. Review.PMID: 8187719 [PubMed - indexed for MEDLINE]Related articlesFree article

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