PubMed

Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats.

Ezendam J, Staedtler F, Pennings J, Vandebriel RJ, Pieters R, Harleman JH, Vos JG.

Environ Health Perspect. 2004 May;112(7):782-91.PMID: 15159207 [PubMed - indexed for MEDLINE]Related articlesFree article

The environmental pollutant hexachlorobenzene causes eosinophilic and granulomatous inflammation and in vitro airways hyperreactivity in the Brown Norway rat.

Michielsen C, Zeamari S, Leusink-Muis A, Vos J, Bloksma N.

Arch Toxicol. 2002 May;76(4):236-47. Epub 2002 Mar 13.PMID: 12029387 [PubMed - indexed for MEDLINE]Related articles

Macrophages are involved in hexachlorobenzene-induced adverse immune effects.

Ezendam J, Kosterman K, Spijkerboer H, Bleumink R, Hassing I, van Rooijen N, Vos JG, Pieters R.

Toxicol Appl Pharmacol. 2005 Nov 15;209(1):19-27.PMID: 16271622 [PubMed - indexed for MEDLINE]Related articles

The mercapturic acid biotransformation pathway of hexachlorobenzene is not involved in the induction of splenomegaly, or skin and lung lesions in the Brown Norway rat.

Michielsen C, Boeren S, Rietjens I, van Mil F, Vos J, Bloksma N.

Arch Toxicol. 2000 Dec;74(10):609-17.PMID: 11201668 [PubMed - indexed for MEDLINE]Related articles

Heme metabolism after discontinued hexachlorobenzene administration in rats: possible irreversible changes and biomarker for hexachlorobenzene persistence.

De Catabbi SCB, Aldonatti C, de Viale LC.

Comp Biochem Physiol C Toxicol Pharmacol. 2000 Sep;127(2):165-75.PMID: 11083027 [PubMed - indexed for MEDLINE]Related articles

The role of thymus-dependent T cells in hexachlorobenzene-induced inflammatory skin and lung lesions.

Michielsen CC, Bloksma N, Klatter FA, Rozing J, Vos JG, van Dijk JE.

Toxicol Appl Pharmacol. 1999 Dec 1;161(2):180-91.PMID: 10581212 [PubMed - indexed for MEDLINE]Related articles

Hexachlorobenzene-induced Immunopathology in Brown Norway rats is partly mediated by T cells.

Ezendam J, Hassing I, Bleumink R, Vos JG, Pieters R.

Toxicol Sci. 2004 Mar;78(1):88-95. Epub 2003 Dec 2.PMID: 14657514 [PubMed - indexed for MEDLINE]Related articlesFree article

Hexachlorobenzene-induced alterations on neutral and acidic sphingomyelinases and serine palmitoyltransferase activities. A time course study in two strains of rats.

Billi de Catabbi SC, Setton-Advruj CP, Sterin-Speziale N, San Martín de Viale LC, Cochón AC.

Toxicology. 2000 Aug 21;149(2-3):89-100.PMID: 10967406 [PubMed - indexed for MEDLINE]Related articles

Research articles mechanisms of hexachlorobenzene-induced adverse immune effects in brown norway rats.

Ezendam J, Vos JG, Pieters R.

J Immunotoxicol. 2005 Jul 1;1(3):167-75.PMID: 18958650 [PubMed - in process]Related articles

Hexachlorobenzene triggers apoptosis in rat thyroid follicular cells.

Chiappini F, Alvarez L, Lux-Lantos V, Randi AS, Kleiman de Pisarev DL.

Toxicol Sci. 2009 Apr;108(2):301-10. Epub 2009 Jan 30.PMID: 19182106 [PubMed - indexed for MEDLINE]Related articles

The role of the immune system in hexachlorobenzene-induced toxicity.

Michielsen CC, van Loveren H, Vos JG.

Environ Health Perspect. 1999 Oct;107 Suppl 5:783-92. Review.PMID: 10502545 [PubMed - indexed for MEDLINE]Related articlesFree article

Hexachlorobenzene-induced immunomodulation and skin and lung lesions: a comparison between brown Norway, Lewis, and Wistar rats.

Michielsen CP, Bloksma N, Ultee A, van Mil F, Vos JG.

Toxicol Appl Pharmacol. 1997 May;144(1):12-26.PMID: 9169065 [PubMed - indexed for MEDLINE]Related articles

[Effect of thyroid hormones on the modulation of genetic expression of liver cytosolic malic enzyme, in rats poisoned with hexachlorobenzene]

Loaiza Perez AI, Sancovich HA, Kleiman De Pisarev DL, Randi AS, Seisdedos M, Ferramola De Sancovich AM, Santisteban P.

Acta Physiol Pharmacol Ther Latinoam. 1998;48(3):125-36. Spanish. PMID: 9777035 [PubMed - indexed for MEDLINE]Related articles

Hexachlorobenzene impairs glucose metabolism in a rat model of porphyria cutanea tarda: a mechanistic approach.

Mazzetti MB, Taira MC, Lelli SM, Dascal E, Basabe JC, de Viale LC.

Arch Toxicol. 2004 Jan;78(1):25-33. Epub 2003 Jul 29.PMID: 12898129 [PubMed - indexed for MEDLINE]Related articles

Hexachlorobenzene-induced early changes in ornithine decarboxylase and protein tyrosine kinase activities, polyamines and c-Myc, c-Fos and c-Jun proto-oncogenes in rat liver.

Randi AS, Hernandez S, Alvarez L, Sanchez M, Schwarcz M, Kleiman d Pisarev DL.

Toxicol Sci. 2003 Dec;76(2):291-8. Epub 2003 Nov 4.PMID: 14600289 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune effects of hexachlorobenzene in the rat: role of metabolism in a 13-week feeding study.

Schielen P, Den Besten C, Vos JG, Van Bladeren PJ, Seinen W, Bloksma N.

Toxicol Appl Pharmacol. 1995 Mar;131(1):37-43.PMID: 7878676 [PubMed - indexed for MEDLINE]Related articles

Studies on the mechanism of uroporphyrinogen decarboxylase inhibition in hexachlorobenzene-induced porphyria in the female rat.

Mylchreest E, Charbonneau M.

Toxicol Appl Pharmacol. 1997 Jul;145(1):23-33.PMID: 9221820 [PubMed - indexed for MEDLINE]Related articles

Stimulation of liver heme oxygenase in hexachlorobenzene-induced hepatic porphyria.

Stonard MD, Poli G, De Matteis F.

Arch Toxicol. 1998 May;72(6):355-61.PMID: 9657283 [PubMed - indexed for MEDLINE]Related articles

Decreased gap junctional intercellular communication in hexachlorobenzene-induced gender-specific hepatic tumor formation in the rat.

Plante I, Charbonneau M, Cyr DG.

Carcinogenesis. 2002 Jul;23(7):1243-9.PMID: 12117784 [PubMed - indexed for MEDLINE]Related articlesFree article

D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.

Soto A, DelRaso NJ, Schlager JJ, Chan VT.

Toxicology. 2008 Jan 14;243(1-2):177-92. Epub 2007 Oct 23.PMID: 18061331 [PubMed - indexed for MEDLINE]Related articles