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Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors.
Gauger KJ, Kato Y, Haraguchi K, Lehmler HJ, Robertson LW, Bansal R, Zoeller RT.
Environ Health Perspect. 2004 Apr;112(5):516-23.PMID: 15064154 [PubMed - indexed for MEDLINE]Related articlesFree article
Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain.
Zoeller RT, Dowling AL, Vas AA.
Endocrinology. 2000 Jan;141(1):181-9.PMID: 10614638 [PubMed - indexed for MEDLINE]Related articlesFree article
Polychlorinated biphenyls (Aroclor 1254) do not uniformly produce agonist actions on thyroid hormone responses in the developing rat brain.
Bansal R, Zoeller RT.
Endocrinology. 2008 Aug;149(8):4001-8. Epub 2008 Apr 17.PMID: 18420739 [PubMed - indexed for MEDLINE]Related articlesFree article
Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254).
Morse DC, Wehler EK, Wesseling W, Koeman JH, Brouwer A.
Toxicol Appl Pharmacol. 1996 Feb;136(2):269-79.PMID: 8619235 [PubMed - indexed for MEDLINE]Related articles
Polychlorinated biphenyls exert selective effects on cellular composition of white matter in a manner inconsistent with thyroid hormone insufficiency.
Sharlin DS, Bansal R, Zoeller RT.
Endocrinology. 2006 Feb;147(2):846-58. Epub 2005 Nov 10.PMID: 16282356 [PubMed - indexed for MEDLINE]Related articlesFree article
Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells.
Gauger KJ, Giera S, Sharlin DS, Bansal R, Iannacone E, Zoeller RT.
Environ Health Perspect. 2007 Nov;115(11):1623-30.PMID: 18007995 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of a mixture of polychlorinated biphenyls (Aroclor 1254) on the transcriptional activity of thyroid hormone receptor.
Bogazzi F, Raggi F, Ultimieri F, Russo D, Campomori A, McKinney JD, Pinchera A, Bartalena L, Martino E.
J Endocrinol Invest. 2003 Oct;26(10):972-8.PMID: 14759069 [PubMed - indexed for MEDLINE]Related articles
NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).
National Toxicology Program.
Natl Toxicol Program Tech Rep Ser. 2006 Jan;(520):4-246.PMID: 16628245 [PubMed - indexed for MEDLINE]Related articles
Maternal hypothyroidism selectively affects the expression of neuroendocrine-specific protein A messenger ribonucleic acid in the proliferative zone of the fetal rat brain cortex.
Dowling AL, Iannacone EA, Zoeller RT.
Endocrinology. 2001 Jan;142(1):390-9.PMID: 11145602 [PubMed - indexed for MEDLINE]Related articlesFree article
Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat.
Meerts IA, Assink Y, Cenijn PH, Van Den Berg JH, Weijers BM, Bergman A, Koeman JH, Brouwer A.
Toxicol Sci. 2002 Aug;68(2):361-71.PMID: 12151632 [PubMed - indexed for MEDLINE]Related articlesFree article
Maternal thyroid hormone increases HES expression in the fetal rat brain: an effect mimicked by exposure to a mixture of polychlorinated biphenyls (PCBs).
Bansal R, You SH, Herzig CT, Zoeller RT.
Brain Res Dev Brain Res. 2005 Apr 21;156(1):13-22.PMID: 15862623 [PubMed - indexed for MEDLINE]Related articles
NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).
Natl Toxicol Program Tech Rep Ser. 2006 May;(529):4-168.PMID: 16835634 [PubMed - indexed for MEDLINE]Related articles
Endocrine disruptive effects of polychlorinated biphenyls on the thyroid gland in female rats.
Kiliç N, Sandal S, Colakoğlu N, Kutlu S, Seyran A, Yilmaz B.
Tohoku J Exp Med. 2005 Aug;206(4):327-32.PMID: 15997204 [PubMed - indexed for MEDLINE]Related articlesFree article
Congener-specific distribution of polychlorinated biphenyls in brain regions, blood, liver, and fat of adult rats following repeated exposure to Aroclor 1254.
Kodavanti PR, Ward TR, Derr-Yellin EC, Mundy WR, Casey AC, Bush B, Tilson HA.
Toxicol Appl Pharmacol. 1998 Dec;153(2):199-210.PMID: 9878591 [PubMed - indexed for MEDLINE]Related articles
Alterations in gene expression of glutamate receptors and exocytosis-related factors by a hydroxylated-polychlorinated biphenyl in the developing rat brain.
Takahashi M, Negishi T, Imamura M, Sawano E, Kuroda Y, Yoshikawa Y, Tashiro T.
Toxicology. 2009 Mar 4;257(1-2):17-24. Epub 2008 Dec 9.PMID: 19114083 [PubMed - indexed for MEDLINE]Related articles
Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats.
Goldey ES, Kehn LS, Lau C, Rehnberg GL, Crofton KM.
Toxicol Appl Pharmacol. 1995 Nov;135(1):77-88.PMID: 7482542 [PubMed - indexed for MEDLINE]Related articles
Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats.
Morse DC, Groen D, Veerman M, van Amerongen CJ, Koëter HB, Smits van Prooije AE, Visser TJ, Koeman JH, Brouwer A.
Toxicol Appl Pharmacol. 1993 Sep;122(1):27-33.PMID: 8378931 [PubMed - indexed for MEDLINE]Related articles
Environmental chemicals impacting the thyroid: targets and consequences.
Zoeller RT.
Thyroid. 2007 Sep;17(9):811-7. Review.PMID: 17956155 [PubMed - indexed for MEDLINE]Related articles
Repeated exposure of adult rats to Aroclor 1254 causes brain region-specific changes in intracellular Ca2+ buffering and protein kinase C activity in the absence of changes in tyrosine hydroxylase.
Kodavanti PR, Derr-Yellin EC, Mundy WR, Shafer TJ, Herr DW, Barone S, Choksi NY, MacPhail RC, Tilson HA.
Toxicol Appl Pharmacol. 1998 Dec;153(2):186-98.PMID: 9878590 [PubMed - indexed for MEDLINE]Related articles
Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors.
Fritsche E, Cline JE, Nguyen NH, Scanlan TS, Abel J.
Environ Health Perspect. 2005 Jul;113(7):871-6.PMID: 16002375 [PubMed - indexed for MEDLINE]Related articlesFree article
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