PubMed

The molecular mechanisms of arsenic-induced cell transformation and apoptosis.

Dong Z.

Environ Health Perspect. 2002 Oct;110 Suppl 5:757-9.PMID: 12426127 [PubMed - indexed for MEDLINE]Related articlesFree article

Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.

Huang C, Ma WY, Li J, Dong Z.

Cancer Res. 1999 Jul 1;59(13):3053-8.PMID: 10397243 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement of Erk, but not JNK, for arsenite-induced cell transformation.

Huang C, Ma WY, Li J, Goranson A, Dong Z.

J Biol Chem. 1999 May 21;274(21):14595-601.PMID: 10329651 [PubMed - indexed for MEDLINE]Related articlesFree article

The extracellular-signal-regulated protein kinases (Erks) are required for UV-induced AP-1 activation in JB6 cells.

Huang C, Ma WY, Dong Z.

Oncogene. 1999 May 6;18(18):2828-35.PMID: 10362253 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis.

She QB, Huang C, Zhang Y, Dong Z.

Mol Carcinog. 2002 Apr;33(4):244-50.PMID: 11933078 [PubMed - indexed for MEDLINE]Related articles

Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis.

Chen N, Ma W, Huang C, Dong Z.

J Biol Chem. 1999 May 28;274(22):15389-94.PMID: 10336426 [PubMed - indexed for MEDLINE]Related articlesFree article

Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.

She QB, Bode AM, Ma WY, Chen NY, Dong Z.

Cancer Res. 2001 Feb 15;61(4):1604-10.PMID: 11245472 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1.

Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Benzil DL, Whysner J, Albino AP, Murali R, Jhanwar-Uniyal M.

Mol Carcinog. 2006 Jan;45(1):26-37. Erratum in: Mol Carcinog. 2006 Jul;45(7):549. Aggarwal, Bharat A [corrected to Aggarwal, Bharat B]. PMID: 16267831 [PubMed - indexed for MEDLINE]Related articles

Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway.

Qu W, Bortner CD, Sakurai T, Hobson MJ, Waalkes MP.

Carcinogenesis. 2002 Jan;23(1):151-9.PMID: 11756236 [PubMed - indexed for MEDLINE]Related articlesFree article

Arsenic-induced NFkappaB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells.

Huang C, Li J, Ding M, Wang L, Shi X, Castranova V, Vallyathan V, Ju G, Costa M.

Mol Cell Biochem. 2001 Jun;222(1-2):29-34.PMID: 11678607 [PubMed - indexed for MEDLINE]Related articles

Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation.

Watts RG, Huang C, Young MR, Li JJ, Dong Z, Pennie WD, Colburn NH.

Oncogene. 1998 Dec 31;17(26):3493-8.PMID: 10030673 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.

Yang YM, Conaway CC, Chiao JW, Wang CX, Amin S, Whysner J, Dai W, Reinhardt J, Chung FL.

Cancer Res. 2002 Jan 1;62(1):2-7.PMID: 11782348 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.

Xiao D, Singh SV.

Cancer Res. 2002 Jul 1;62(13):3615-9.PMID: 12097262 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells.

Lau AT, Li M, Xie R, He QY, Chiu JF.

Carcinogenesis. 2004 Jan;25(1):21-8. Epub 2003 Sep 26.PMID: 14514659 [PubMed - indexed for MEDLINE]Related articlesFree article

Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation.

Dhar A, Hu J, Reeves R, Resar LM, Colburn NH.

Oncogene. 2004 May 27;23(25):4466-76.PMID: 15064752 [PubMed - indexed for MEDLINE]Related articles

Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.

Li Y, Mao Y, Brandt-Rauf PW, Williams AC, Fine RL.

Mol Cancer Ther. 2005 Jun;4(6):901-9.PMID: 15956247 [PubMed - indexed for MEDLINE]Related articlesFree article

10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status.

Ghose S, Oleinik NV, Krupenko NI, Krupenko SA.

Mol Cancer Res. 2009 Jan;7(1):99-107.PMID: 19147541 [PubMed - indexed for MEDLINE]Related articles

Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.

Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C.

Cancer Res. 2005 Aug 1;65(15):6601-11.PMID: 16061640 [PubMed - indexed for MEDLINE]Related articlesFree article

JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate.

Huang C, Li J, Ma WY, Dong Z.

J Biol Chem. 1999 Oct 15;274(42):29672-6.PMID: 10514437 [PubMed - indexed for MEDLINE]Related articlesFree article

The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine.

Fan M, Goodwin ME, Birrer MJ, Chambers TC.

Cancer Res. 2001 Jun 1;61(11):4450-8.PMID: 11389075 [PubMed - indexed for MEDLINE]Related articlesFree article