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Pharmacokinetics of toxic chemicals in breast milk: use of PBPK models to predict infant exposure.

Clewell RA, Gearhart JM.

Environ Health Perspect. 2002 Jun;110(6):A333-7.PMID: 12055064 [PubMed - indexed for MEDLINE]Related articlesFree article

Proposed PBPK model to predict infant exposure to toxic chemicals in breast milk.

Soldin OP.

Environ Health Perspect. 2002 Nov;110(11):A663; author reply A663-4. No abstract available. PMID: 12440394 [PubMed - indexed for MEDLINE]Related articlesFree article

The use of physiologically based models to integrate diverse data sets and reduce uncertainty in the prediction of perchlorate and iodide kinetics across life stages and species.

Clewell RA, Merrill EA, Robinson PJ.

Toxicol Ind Health. 2001 Jun;17(5-10):210-22.PMID: 12539865 [PubMed - indexed for MEDLINE]Related articles

Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling.

Clewell RA, Merrill EA, Yu KO, Mahle DA, Sterner TR, Fisher JW, Gearhart JM.

Toxicol Sci. 2003 Aug;74(2):416-36. Epub 2003 Jun 12.PMID: 12805655 [PubMed - indexed for MEDLINE]Related articlesFree article

Predicting fetal perchlorate dose and inhibition of iodide kinetics during gestation: a physiologically-based pharmacokinetic analysis of perchlorate and iodide kinetics in the rat.

Clewell RA, Merrill EA, Yu KO, Mahle DA, Sterner TR, Mattie DR, Robinson PJ, Fisher JW, Gearhart JM.

Toxicol Sci. 2003 Jun;73(2):235-55. Epub 2003 Apr 15.PMID: 12700398 [PubMed - indexed for MEDLINE]Related articlesFree article

Perchlorate and radioiodide kinetics across life stages in the human: using PBPK models to predict dosimetry and thyroid inhibition and sensitive subpopulations based on developmental stage.

Clewell RA, Merrill EA, Gearhart JM, Robinson PJ, Sterner TR, Mattie DR, Clewell HJ 3rd.

J Toxicol Environ Health A. 2007 Mar 1;70(5):408-28.PMID: 17454566 [PubMed - indexed for MEDLINE]Related articles

"Occupational" exposure of infants to toxic chemicals via breast milk.

Byczkowski JZ, Gearhart JM, Fisher JW.

Nutrition. 1994 Jan-Feb;10(1):43-8. Review.PMID: 8199422 [PubMed - indexed for MEDLINE]Related articles

PBPK predictions of perchlorate distribution and its effect on thyroid uptake of radioiodide in the male rat.

Merrill EA, Clewell RA, Gearhart JM, Robinson PJ, Sterner TR, Yu KO, Mattie DR, Fisher JW.

Toxicol Sci. 2003 Jun;73(2):256-69. Epub 2003 Apr 15.PMID: 12700397 [PubMed - indexed for MEDLINE]Related articlesFree article

A computer program linking physiologically based pharmacokinetic model with cancer risk assessment for breast-fed infants.

Byczkowski JZ, Fisher JW.

Comput Methods Programs Biomed. 1995 Feb;46(2):155-63.PMID: 7796584 [PubMed - indexed for MEDLINE]Related articles

Infant exposure to dioxin-like compounds in breast milk.

Lorber M, Phillips L.

Environ Health Perspect. 2002 Jun;110(6):A325-32.PMID: 12055063 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiologically based pharmacokinetic modeling of persistent organic pollutants for lifetime exposure assessment: a new tool in breast cancer epidemiologic studies.

Verner MA, Charbonneau M, López-Carrillo L, Haddad S.

Environ Health Perspect. 2008 Jul;116(7):886-92.PMID: 18629310 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimates of exposures to perchlorate from consumption of human milk, dairy milk, and water, and comparison to current reference dose.

Baier-Anderson C, Blount BC, Lakind JS, Naiman DQ, Wilbur SB, Tan S.

J Toxicol Environ Health A. 2006 Feb;69(3-4):319-30.PMID: 16407090 [PubMed - indexed for MEDLINE]Related articles

Physiological modeling and extrapolation of pharmacokinetic interactions from binary to more complex chemical mixtures.

Krishnan K, Haddad S, Béliveau M, Tardif R.

Environ Health Perspect. 2002 Dec;110 Suppl 6:989-94. Review.PMID: 12634130 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment.

Andersen ME.

Toxicol Lett. 1995 Sep;79(1-3):35-44. Review.PMID: 7570672 [PubMed - indexed for MEDLINE]Related articles

Environmental chemicals in human milk: a review of levels, infant exposures and health, and guidance for future research.

LaKind JS, Amina Wilkins A, Berlin CM Jr.

Toxicol Appl Pharmacol. 2004 Jul 15;198(2):184-208. Review.PMID: 15236953 [PubMed - indexed for MEDLINE]Related articles

Infant exposure to chemicals in breast milk in the United States: what we need to learn from a breast milk monitoring program.

LaKind JS, Berlin CM, Naiman DQ.

Environ Health Perspect. 2001 Jan;109(1):75-88. Review.PMID: 11171529 [PubMed - indexed for MEDLINE]Related articlesFree article

A distributed parameter physiologically-based pharmacokinetic model for dermal and inhalation exposure to volatile organic compounds.

Roy A, Weisel CP, Lioy PJ, Georgopoulos PG.

Risk Anal. 1996 Apr;16(2):147-60.PMID: 8638037 [PubMed - indexed for MEDLINE]Related articles

Lactational transfer of volatile chemicals in breast milk.

Fisher J, Mahle D, Bankston L, Greene R, Gearhart J.

Am Ind Hyg Assoc J. 1997 Jun;58(6):425-31.PMID: 9183837 [PubMed - indexed for MEDLINE]Related articles

Predicting maternal rat and pup exposures: how different are they?

Yoon M, Barton HA.

Toxicol Sci. 2008 Mar;102(1):15-32. Epub 2007 Nov 17.PMID: 18024990 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation.

Gentry PR, Covington TR, Clewell HJ 3rd.

Regul Toxicol Pharmacol. 2003 Aug;38(1):1-16.PMID: 12878049 [PubMed - indexed for MEDLINE]Related articles