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The Spanish toxic oil syndrome 20 years after its onset: a multidisciplinary review of scientific knowledge.

Gelpí E, de la Paz MP, Terracini B, Abaitua I, de la Cámara AG, Kilbourne EM, Lahoz C, Nemery B, Philen RM, Soldevilla L, Tarkowski S; WHO/CISAT Scientific Committee for the Toxic Oil Syndrome. Centro de Investigación para el Síndrome del Aceite Tóxico.

Environ Health Perspect. 2002 May;110(5):457-64. Review.PMID: 12003748 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxic oil syndrome: the perspective after 20 years.

Posada de la Paz M, Philen RM, Borda AI.

Epidemiol Rev. 2001;23(2):231-47. Review.PMID: 12192735 [PubMed - indexed for MEDLINE]Related articlesFree article

Biotransformation of 3-(phenylamino)-1,2-propanediol to 3-(phenylamino)alanine: a chemical link between toxic oil syndrome and eosinophilia-myalgia syndrome.

Mayeno AN, Benson LM, Naylor S, Colberg-Beers M, Puchalski JT, Gleich GJ.

Chem Res Toxicol. 1995 Oct-Nov;8(7):911-6.PMID: 8555405 [PubMed - indexed for MEDLINE]Related articles

On the generation and outcome of 3-(N-phenylamino)propane-1,2-diol derivatives in deodorized model oils related to toxic oil syndrome.

Morató A, Escabrós J, Manich A, Reig N, Castaño Y, Abián J, Messeguer A.

Chem Res Toxicol. 2005 Apr;18(4):665-74.PMID: 15833026 [PubMed - indexed for MEDLINE]Related articles

Possible etiologic agents for toxic oil syndrome: fatty acid esters of 3-(N-phenylamino)-1,2-propanediol.

Hill RH Jr, Schurz HH, Posada de la Paz M, Abaitua Borda I, Philen RM, Kilbourne EM, Head SL, Bailey SL, Driskell WJ, Barr JR, et al.

Arch Environ Contam Toxicol. 1995 Feb;28(2):259-64.PMID: 7710294 [PubMed - indexed for MEDLINE]Related articles

A comparison of the acute pathology induced by 3-phenylamino-1,2-propanediol (PAP) and its mono-oleoyl ester in rodents with the toxic oil syndrome in man.

Carthew P, Edwards RE, Dorman BM, Verschoyle RD.

Hum Exp Toxicol. 1995 Feb;14(2):217-20.PMID: 7779449 [PubMed - indexed for MEDLINE]Related articles

Toxic oil syndrome and eosinophilia-myalgia syndrome: May 8-10, 1991, World Health Organization meeting report.

Philen RM, Posada M.

Semin Arthritis Rheum. 1993 Oct;23(2):104-24. Review.PMID: 8266108 [PubMed - indexed for MEDLINE]Related articles

Products of aniline and triglycerides in oil samples associated with the toxic oil syndrome.

Schurz HH, Hill RH, Posada de la Paz M, Philen RM, Borda IA, Bailey SL, Needham LL.

Chem Res Toxicol. 1996 Sep;9(6):1001-6.PMID: 8870988 [PubMed - indexed for MEDLINE]Related articles

Toxic oil syndrome mortality: the first 13 years.

Abaitua Borda I, Philen RM, Posada de la Paz M, Gómez de la Cámara A, Díez Ruiz-Navarro M, Giménez Ribota O, Alvargonzález Soldevilla J, Terracini B, Severiano Peña S, Fuentes Leal C, Kilbourne EM.

Int J Epidemiol. 1998 Dec;27(6):1057-63.PMID: 10024203 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemical correlates of pathogenicity of oils related to the toxic oil syndrome epidemic in Spain.

Kilbourne EM, Bernert JT Jr, Posada de la Paz M, Hill RH Jr, Abaitua Borda I, Kilbourne BW, Zack MM.

Am J Epidemiol. 1988 Jun;127(6):1210-27.PMID: 3369420 [PubMed - indexed for MEDLINE]Related articles

Endocytosis and intracellular trafficking of fatty acid esters of phenylaminopropanediol, the putative etiologic agents of the toxic oil syndrome (TOS).

Gonzalez JB, Orth M, Schaefer M, Tauber R.

Toxicol Lett. 2006 Jun 1;163(3):206-12. Epub 2005 Dec 15.PMID: 16343824 [PubMed - indexed for MEDLINE]Related articles

Absorption and effects of 3-(N-phenylamino)-1,2-propanediol esters in relation to toxic oil syndrome.

Closa D, Folch E, Calaf RE, Abián J, Roselló-Catafau J, Gelpí E.

Lipids. 2001 Oct;36(10):1125-33.PMID: 11768157 [PubMed - indexed for MEDLINE]Related articles

Biotransformation and clearance of 3-(phenylamino)propane-1,2-diol, a compound present in samples related to toxic oil syndrome, in C57BL/6 and A/J mice.

Ladona MG, Bujons J, Messeguer A, Ampurdanés C, Morató A, Corbella J.

Chem Res Toxicol. 1999 Dec;12(12):1127-37.PMID: 10604860 [PubMed - indexed for MEDLINE]Related articles

Epidemiologic evidence for a new class of compounds associated with toxic oil syndrome.

Posada de la Paz M, Philen RM, Schurz H, Hill RH Jr, Giménez Ribota O, Gómez de la Camara A, Kilbourne EM, Abaitua I.

Epidemiology. 1999 Mar;10(2):130-4.PMID: 10069247 [PubMed - indexed for MEDLINE]Related articles

Toxic oil syndrome: a current clinical and epidemiologic summary, including comparisons with the eosinophilia-myalgia syndrome.

Kilbourne EM, Posada de la Paz M, Abaitua Borda I, Diez Ruiz-Navarro M, Philen RM, Falk H.

J Am Coll Cardiol. 1991 Sep;18(3):711-7.PMID: 1869734 [PubMed - indexed for MEDLINE]Related articles

Toxic oil syndrome: traceback of the toxic oil and evidence for a point source epidemic.

Posada de la Paz M, Philen RM, Borda IA, Sicilia Socias JM, Gómez de la Cámara A, Kilbourne EM.

Food Chem Toxicol. 1996 Mar;34(3):251-7.PMID: 8621106 [PubMed - indexed for MEDLINE]Related articles

Factors associated with pathogenicity of oils related to the toxic oil syndrome epidemic in Spain.

Posada de la Paz M, Philen RM, Abaitua Borda I, Diez Ruiz-Navarro M, Abraira Santos V, Pozo Rodríguez F, Pla Mestre R, Pollán Santamaría M, Sicilia Socias JM, Azpeitia Gamazo P, et al.

Epidemiology. 1994 Jul;5(4):404-9.PMID: 7918809 [PubMed - indexed for MEDLINE]Related articles

DR2 antigens are associated with severity of disease in toxic oil syndrome (TOS).

Cárdaba B, Ezendam J, Gallardo S, del Pozo V, Izquierdo M, Martín C, Cortegano I, Aceituno E, Rojo M, Arrieta I, Palomino P, Posada M, Lahoz C.

Tissue Antigens. 2000 Feb;55(2):110-7.PMID: 10746782 [PubMed - indexed for MEDLINE]Related articles

Immunoglobulin and autoantibody responses in MRL/lpr mice treated with 'toxic oils'.

Koller LD, Stang BV, Hall JA, Posada de la Paz M, Ruiz Mendez MV.

Toxicology. 2002 Sep 2;178(2):119-33.PMID: 12160619 [PubMed - indexed for MEDLINE]Related articles

Toxic oil syndrome. A long-term follow-up of a cohort of 332 patients.

Alonso-Ruiz A, Calabozo M, Perez-Ruiz F, Mancebo L.

Medicine (Baltimore). 1993 Sep;72(5):285-95.PMID: 8412642 [PubMed - indexed for MEDLINE]Related articles