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Biologically based dose-response model for liver tumors induced by trichloroethylene.

Chen CW.

Environ Health Perspect. 2000 May;108 Suppl 2:335-42.PMID: 10807563 [PubMed - indexed for MEDLINE]Related articlesFree article

Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.

Bull RJ.

Environ Health Perspect. 2000 May;108 Suppl 2:241-59. Review.PMID: 10807555 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.

Bull RJ, Sasser LB, Lei XC.

Toxicology. 2004 Jul 1;199(2-3):169-83.PMID: 15147791 [PubMed - indexed for MEDLINE]Related articles

Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene.

Bull RJ, Orner GA, Cheng RS, Stillwell L, Stauber AJ, Sasser LB, Lingohr MK, Thrall BD.

Toxicol Appl Pharmacol. 2002 Jul 1;182(1):55-65.PMID: 12127263 [PubMed - indexed for MEDLINE]Related articles

Dissimilar characteristics of N-methyl-N-nitrosourea-initiated foci and tumors promoted by dichloroacetic acid or trichloroacetic acid in the liver of female B6C3F1 mice.

Latendresse JR, Pereira MA.

Toxicol Pathol. 1997 Sep-Oct;25(5):433-40.PMID: 9323830 [PubMed - indexed for MEDLINE]Related articles

Dose-response analyses of the carcinogenic effects of trichloroethylene in experimental animals.

Rhomberg LR.

Environ Health Perspect. 2000 May;108 Suppl 2:343-58. Review.PMID: 10807564 [PubMed - indexed for MEDLINE]Related articlesFree article

Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate.

Larson JL, Bull RJ.

Toxicol Appl Pharmacol. 1992 Aug;115(2):278-85.PMID: 1641861 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites.

Corton JC.

Crit Rev Toxicol. 2008;38(10):857-75. Review.PMID: 18821149 [PubMed - indexed for MEDLINE]Related articles

Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene.

Moore MM, Harrington-Brock K.

Environ Health Perspect. 2000 May;108 Suppl 2:215-23. Review.PMID: 10807553 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice.

Pereira MA, Kramer PM, Conran PB, Tao L.

Carcinogenesis. 2001 Sep;22(9):1511-9.PMID: 11532874 [PubMed - indexed for MEDLINE]Related articlesFree article

The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver.

Herren-Freund SL, Pereira MA, Khoury MD, Olson G.

Toxicol Appl Pharmacol. 1987 Sep 15;90(2):183-9.PMID: 3629594 [PubMed - indexed for MEDLINE]Related articles

Loss of heterozygosity on chromosome 6 in dichloroacetic acid and trichloroacetic acid-induced liver tumors in female B6C3F1 mice.

Tao L, Li K, Kramer PM, Pereira MA.

Cancer Lett. 1996 Nov 29;108(2):257-61.PMID: 8973603 [PubMed - indexed for MEDLINE]Related articles

Dichloroacetate (DCA) dosimetry: interpreting DCA-induced liver cancer dose response and the potential for DCA to contribute to trichloroethylene-induced liver cancer.

Barton HA, Bull R, Schultz I, Andersen ME.

Toxicol Lett. 1999 May 20;106(1):9-21.PMID: 10378446 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.

Kim S, Kim D, Pollack GM, Collins LB, Rusyn I.

Toxicol Appl Pharmacol. 2009 Jul 1;238(1):90-9. Epub 2009 May 3.PMID: 19409406 [PubMed - indexed for MEDLINE]Related articles

Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice.

Templin MV, Parker JC, Bull RJ.

Toxicol Appl Pharmacol. 1993 Nov;123(1):1-8. Erratum in: Toxicol Appl Pharmacol 1995 Jul;133(1):177. PMID: 8236248 [PubMed - indexed for MEDLINE]Related articles

Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.

Caldwell JC, Keshava N.

Environ Health Perspect. 2006 Sep;114(9):1457-63. Review.PMID: 16966105 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of trichloroethylene and its metabolites, dichloroacetic acid and trichloroacetic acid, on the methylation and expression of c-Jun and c-Myc protooncogenes in mouse liver: prevention by methionine.

Tao L, Yang S, Xie M, Kramer PM, Pereira MA.

Toxicol Sci. 2000 Apr;54(2):399-407.PMID: 10774822 [PubMed - indexed for MEDLINE]Related articlesFree article

Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.

Hack CE, Chiu WA, Jay Zhao Q, Clewell HJ.

Regul Toxicol Pharmacol. 2006 Oct;46(1):63-83. Epub 2006 Aug 4.PMID: 16889879 [PubMed - indexed for MEDLINE]Related articles

Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice.

Tao L, Kramer PM, Ge R, Pereira MA.

Toxicol Sci. 1998 Jun;43(2):139-44.PMID: 9710955 [PubMed - indexed for MEDLINE]Related articles

A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.

Abbas R, Fisher JW.

Toxicol Appl Pharmacol. 1997 Nov;147(1):15-30.PMID: 9356303 [PubMed - indexed for MEDLINE]Related articles