PubMed

Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics.

Bois FY.

Environ Health Perspect. 2000 May;108 Suppl 2:307-16.PMID: 10807560 [PubMed - indexed for MEDLINE]Related articlesFree article

Statistical analysis of Fisher et al. PBPK model of trichloroethylene kinetics.

Bois FY.

Environ Health Perspect. 2000 May;108 Suppl 2:275-82.PMID: 10807558 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach.

Chiu WA, Okino MS, Evans MV.

Toxicol Appl Pharmacol. 2009 Nov 15;241(1):36-60. Epub 2009 Aug 4.PMID: 19660485 [PubMed - indexed for MEDLINE]Related articles

Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.

Hack CE, Chiu WA, Jay Zhao Q, Clewell HJ.

Regul Toxicol Pharmacol. 2006 Oct;46(1):63-83. Epub 2006 Aug 4.PMID: 16889879 [PubMed - indexed for MEDLINE]Related articles

A trichloroethylene risk assessment using a Monte Carlo analysis of parameter uncertainty in conjunction with physiologically-based pharmacokinetic modeling.

Cronin WJ 4th, Oswald EJ, Shelley ML, Fisher JW, Flemming CD.

Risk Anal. 1995 Oct;15(5):555-65.PMID: 7501875 [PubMed - indexed for MEDLINE]Related articles

Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.

Clewell HJ 3rd, Gentry PR, Covington TR, Gearhart JM.

Environ Health Perspect. 2000 May;108 Suppl 2:283-305. Review.PMID: 10807559 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform.

Allen BC, Covington TR, Clewell HJ.

Toxicology. 1996 Jul 17;111(1-3):289-303.PMID: 8711743 [PubMed - indexed for MEDLINE]Related articles

Trichloroethylene cancer risk: simplified calculation of PBPK-based MCLs for cytotoxic end points.

Bogen KT, Gold LS.

Regul Toxicol Pharmacol. 1997 Feb;25(1):26-42. Review.PMID: 9056499 [PubMed - indexed for MEDLINE]Related articles

Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene.

Liao KH, Tan YM, Clewell HJ 3rd.

Risk Anal. 2007 Oct;27(5):1223-36.PMID: 18076492 [PubMed - indexed for MEDLINE]Related articles

Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly.

Evans MV, Chiu WA, Okino MS, Caldwell JC.

Toxicol Appl Pharmacol. 2009 May 1;236(3):329-40. Epub 2009 Feb 26.PMID: 19249323 [PubMed - indexed for MEDLINE]Related articles

Revised assessment of cancer risk to dichloromethane: part I Bayesian PBPK and dose-response modeling in mice.

Marino DJ, Clewell HJ, Gentry PR, Covington TR, Hack CE, David RM, Morgott DA.

Regul Toxicol Pharmacol. 2006 Jun;45(1):44-54. Epub 2006 Jan 25.PMID: 16442684 [PubMed - indexed for MEDLINE]Related articles

The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene.

Covington TR, Robinan Gentry P, Van Landingham CB, Andersen ME, Kester JE, Clewell HJ.

Regul Toxicol Pharmacol. 2007 Feb;47(1):1-18. Epub 2006 Aug 9.PMID: 16901594 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans.

Allen BC, Fisher JW.

Risk Anal. 1993 Feb;13(1):71-86.PMID: 8451462 [PubMed - indexed for MEDLINE]Related articles

Trichloroethylene and cancer: epidemiologic evidence

Scott CS, Cogliano VJ.

Environ Health Perspect. 2000 May;108 Suppl 2:159-60.PMID: 10807549 [PubMed - as supplied by publisher]Related articles

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE).

Gearhart JM, Mahle DA, Greene RJ, Seckel CS, Flemming CD, Fisher JW, Clewell HJ 3rd.

Toxicol Lett. 1993 May;68(1-2):131-44.PMID: 8516760 [PubMed - indexed for MEDLINE]Related articles

Assessing the reliability of PBPK models using data from methyl chloride-exposed, non-conjugating human subjects.

Jonsson F, Bois FY, Johanson G.

Arch Toxicol. 2001 Jun;75(4):189-99.PMID: 11482516 [PubMed - indexed for MEDLINE]Related articles

Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.

Greenberg MS, Burton GA, Fisher JW.

Toxicol Appl Pharmacol. 1999 Feb 1;154(3):264-78.PMID: 9931286 [PubMed - indexed for MEDLINE]Related articles

Reassessing benzene risks using internal doses and Monte-Carlo uncertainty analysis.

Cox LA Jr.

Environ Health Perspect. 1996 Dec;104 Suppl 6:1413-29.PMID: 9118928 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue dosimetry expansion and cross-validation of rat and mouse physiologically based pharmacokinetic models for trichloroethylene.

Keys DA, Bruckner JV, Muralidhara S, Fisher JW.

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An example of model structure differences using sensitivity analyses in physiologically based pharmacokinetic models of trichloroethylene in humans.

Yokley KA, Evans MV.

Bull Math Biol. 2007 Nov;69(8):2591-625. Epub 2007 Sep 26.PMID: 17896160 [PubMed - indexed for MEDLINE]Related articles