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    Results: 1 to 20 of 266

    1.

    Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene.

    Moore MM, Harrington-Brock K.

    Environ Health Perspect. 2000 May;108 Suppl 2:215-23. Review.PMID: 10807553 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.

    Bull RJ.

    Environ Health Perspect. 2000 May;108 Suppl 2:241-59. Review.PMID: 10807555 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.

    Kim S, Kim D, Pollack GM, Collins LB, Rusyn I.

    Toxicol Appl Pharmacol. 2009 Jul 1;238(1):90-9. Epub 2009 May 3.PMID: 19409406 [PubMed - indexed for MEDLINE]Related articles

    4.

    Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.

    Caldwell JC, Keshava N.

    Environ Health Perspect. 2006 Sep;114(9):1457-63. Review.PMID: 16966105 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.

    Kim S, Collins LB, Boysen G, Swenberg JA, Gold A, Ball LM, Bradford BU, Rusyn I.

    Toxicology. 2009 Aug 21;262(3):230-8. Epub 2009 Jun 21.PMID: 19549554 [PubMed - indexed for MEDLINE]Related articles

    6.

    Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.

    Clewell HJ, Andersen ME.

    Crit Rev Toxicol. 2004 Sep-Oct;34(5):385-445. Review.PMID: 15560567 [PubMed - indexed for MEDLINE]Related articles

    7.

    Modes of action of trichloroethylene for kidney tumorigenesis.

    Lash LH, Parker JC, Scott CS.

    Environ Health Perspect. 2000 May;108 Suppl 2:225-40. Review.PMID: 10807554 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites.

    Corton JC.

    Crit Rev Toxicol. 2008;38(10):857-75. Review.PMID: 18821149 [PubMed - indexed for MEDLINE]Related articles

    9.

    Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.

    Clewell HJ 3rd, Gentry PR, Covington TR, Gearhart JM.

    Environ Health Perspect. 2000 May;108 Suppl 2:283-305. Review.PMID: 10807559 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Difficulty of mode of action determination for trichloroethylene: An example of complex interactions of metabolites and other chemical exposures.

    Caldwell JC, Keshava N, Evans MV.

    Environ Mol Mutagen. 2008 Mar;49(2):142-54. Review.PMID: 17973308 [PubMed - indexed for MEDLINE]Related articles

    11.

    Trichloroethylene and cancer: epidemiologic evidence

    Scott CS, Cogliano VJ.

    Environ Health Perspect. 2000 May;108 Suppl 2:159-60.PMID: 10807549 [PubMed - as supplied by publisher]Related articles

    12.

    Biologically based dose-response model for liver tumors induced by trichloroethylene.

    Chen CW.

    Environ Health Perspect. 2000 May;108 Suppl 2:335-42.PMID: 10807563 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Mutagenicity of three disinfection by-products: di- and trichloroacetic acid and chloral hydrate in L5178Y/TK +/- (-)3.7.2C mouse lymphoma cells.

    Harrington-Brock K, Doerr CL, Moore MM.

    Mutat Res. 1998 Mar 30;413(3):265-76.PMID: 9651541 [PubMed - indexed for MEDLINE]Related articles

    14.

    Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene.

    Lock EA, Barth JL, Argraves SW, Schnellmann RG.

    Toxicol Appl Pharmacol. 2006 Oct 15;216(2):319-30. Epub 2006 Jun 8.PMID: 16844155 [PubMed - indexed for MEDLINE]Related articles

    15.

    Key scientific issues in the health risk assessment of trichloroethylene.

    Chiu WA, Caldwell JC, Keshava N, Scott CS.

    Environ Health Perspect. 2006 Sep;114(9):1445-9. Review.PMID: 16966103 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.

    Abbas R, Fisher JW.

    Toxicol Appl Pharmacol. 1997 Nov;147(1):15-30.PMID: 9356303 [PubMed - indexed for MEDLINE]Related articles

    17.

    Use of genetic toxicology data in U.S. EPA risk assessment: the mercury study report as an example.

    Schoeny R.

    Environ Health Perspect. 1996 May;104 Suppl 3:663-73.PMID: 8781402 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid.

    Delinsky AD, Bruckner JV, Bartlett MG.

    Biomed Chromatogr. 2005 Oct;19(8):617-39. Review.PMID: 15828053 [PubMed - indexed for MEDLINE]Related articles

    19.

    Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.

    Keshava N, Caldwell JC.

    Environ Health Perspect. 2006 Sep;114(9):1464-70. Review.PMID: 16966106 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Trichloroethylene cancer epidemiology: a consideration of select issues.

    Scott CS, Chiu WA.

    Environ Health Perspect. 2006 Sep;114(9):1471-8. Review.PMID: 16966107 [PubMed - indexed for MEDLINE]Related articlesFree article

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