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    Results: 1 to 20 of 169

    1.

    Initiation of autoimmunity by a reactive metabolite of a lupus-inducing drug in the thymus.

    Rubin RL, Kretz-Rommel A.

    Environ Health Perspect. 1999 Oct;107 Suppl 5:803-6. Review.PMID: 10502546 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Autoimmunity caused by disruption of central T cell tolerance. A murine model of drug-induced lupus.

    Kretz-Rommel A, Duncan SR, Rubin RL.

    J Clin Invest. 1997 Apr 15;99(8):1888-96.PMID: 9109433 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs.

    Rubin RL.

    Clin Biochem. 1992 Jun;25(3):223-34.PMID: 1633638 [PubMed - indexed for MEDLINE]Related articles

    4.

    Persistence of autoreactive T cell drive is required to elicit anti-chromatin antibodies in a murine model of drug-induced lupus.

    Kretz-Rommel A, Rubin RL.

    J Immunol. 1999 Jan 15;162(2):813-20.PMID: 9916703 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Drug-induced lupus.

    Rubin RL.

    Toxicology. 2005 Apr 15;209(2):135-47. Review.PMID: 15767026 [PubMed - indexed for MEDLINE]Related articles

    6.

    A metabolite of the lupus-inducing drug procainamide prevents anergy induction in T cell clones.

    Kretz-Rommel A, Rubin RL.

    J Immunol. 1997 May 1;158(9):4465-70.PMID: 9127012 [PubMed - indexed for MEDLINE]Related articles

    7.

    Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.

    Jiang X, Khursigara G, Rubin RL.

    Science. 1994 Nov 4;266(5186):810-3.PMID: 7973636 [PubMed - indexed for MEDLINE]Related articles

    8.

    Thymus function in drug-induced lupus.

    Rubin RL, Salomon DR, Guerrero RS.

    Lupus. 2001;10(11):795-801.PMID: 11789489 [PubMed - indexed for MEDLINE]Related articles

    9.

    Early cellular events in systemic autoimmunity driven by chromatin-reactive T cells.

    Kretz-Rommel A, Rubin RL.

    Cell Immunol. 2001 Mar 15;208(2):125-36.PMID: 11333145 [PubMed - indexed for MEDLINE]Related articles

    10.

    Metabolism of drugs by activated leukocytes: implications for drug-induced lupus and other drug hypersensitivity reactions.

    Uetrecht J.

    Adv Exp Med Biol. 1991;283:121-32. Review.PMID: 2068978 [PubMed - indexed for MEDLINE]Related articles

    11.

    Metabolism of procainamide to the cytotoxic hydroxylamine by neutrophils activated in vitro.

    Rubin RL, Curnutte JT.

    J Clin Invest. 1989 Apr;83(4):1336-43.PMID: 2539397 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    A nondeletional mechanism for central T-cell tolerance.

    Rubin RL, Kretz-Rommel A.

    Crit Rev Immunol. 2001;21(1-3):29-40. Review.PMID: 11642611 [PubMed - indexed for MEDLINE]Related articles

    13.

    Etiology and mechanisms of drug-induced lupus.

    Rubin RL.

    Curr Opin Rheumatol. 1999 Sep;11(5):357-63. Review.PMID: 10503655 [PubMed - indexed for MEDLINE]Related articles

    14.

    DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.

    Zhou Y, Lu Q.

    Autoimmun Rev. 2008 May;7(5):376-83. Epub 2008 Apr 4. Review.PMID: 18486925 [PubMed - indexed for MEDLINE]Related articles

    15.

    Prevention and control of reciprocal T-B cell diversification: implications for lupus-like autoimmunity.

    Singh RR.

    Mol Immunol. 2004 Feb;40(14-15):1137-45. Review.PMID: 15036920 [PubMed - indexed for MEDLINE]Related articles

    16.

    Disruption of positive selection of thymocytes causes autoimmunity.

    Kretz-Rommel A, Rubin RL.

    Nat Med. 2000 Mar;6(3):298-305.PMID: 10700232 [PubMed - indexed for MEDLINE]Related articles

    17.

    The Mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus.

    Shao WH, Eisenberg RA, Cohen PL.

    J Immunol. 2008 Jun 1;180(11):7728-35.PMID: 18490777 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    New insights from murine lupus: disassociation of autoimmunity and end organ damage and the role of T cells.

    Bagavant H, Fu SM.

    Curr Opin Rheumatol. 2005 Sep;17(5):523-8. Review.PMID: 16093828 [PubMed - indexed for MEDLINE]Related articles

    19.

    Procainamide, a drug causing lupus, induces prostaglandin H synthase-2 and formation of T cell-sensitizing drug metabolites in mouse macrophages.

    Goebel C, Vogel C, Wulferink M, Mittmann S, Sachs B, Schraa S, Abel J, Degen G, Uetrecht J, Gleichmann E.

    Chem Res Toxicol. 1999 Jun;12(6):488-500.PMID: 10368311 [PubMed - indexed for MEDLINE]Related articles

    20.

    DNA methylation and autoimmune disease.

    Richardson B.

    Clin Immunol. 2003 Oct;109(1):72-9. Review.PMID: 14585278 [PubMed - indexed for MEDLINE]Related articles

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