RecName: Full=Sialic acid-binding Ig-like lectin 12; Short=Siglec-12; - Protein

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Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization. [Front Cell Neurosci. 2023]
Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization.
Schröder LJ, Thiesler H, Gretenkort L, Möllenkamp TM, Stangel M, Gudi V, Hildebrandt H. Front Cell Neurosci. 2023; 17:1207540. Epub 2023 Jul 10.
Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. [Sci Transl Med. 2023]
Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma.
Schmassmann P, Roux J, Buck A, Tatari N, Hogan S, Wang J, Rodrigues Mantuano N, Wieboldt R, Lee S, Snijder B, et al. Sci Transl Med. 2023 Jul 19; 15(705):eadf5302. Epub 2023 Jul 19.
The prognostic impact of SIGLEC5-induced impairment of CD8(+) T cell activation in sepsis. [EBioMedicine. 2023]
The prognostic impact of SIGLEC5-induced impairment of CD8(+) T cell activation in sepsis.
Lozano-Rodríguez R, Avendaño-Ortíz J, Montalbán-Hernández K, Ruiz-Rodríguez JC, Ferrer R, Martín-Quirós A, Maroun-Eid C, González-López JJ, Fàbrega A, Terrón-Arcos V, et al. EBioMedicine. 2023 Nov; 97:104841. Epub 2023 Oct 25.

RefSeq protein isoforms
See 5 reference sequence protein isoforms for the Siglece gene.

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Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
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RecName: Full=Sialic acid-binding Ig-like lectin 12; Short=Siglec-12; AltName: F...
RecName: Full=Sialic acid-binding Ig-like lectin 12; Short=Siglec-12; AltName: Full=Myeloid inhibitory siglec; Short=MIS; AltName: Full=Sialic acid-binding Ig-like lectin 5; Short=Siglec-5; AltName: Full=Sialic acid-binding Ig-like lectin E; Short=Siglec-E; Short=mSiglec-E; AltName: Full=Sialic acid-binding Ig-like lectin-like 1; Short=Siglec-L1; Flags: Precursor
gi|341942120|sp|Q91Y57.3|SIG12_MOUS

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