Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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NR0B2, Homo sapiens
nuclear receptor subfamily 0, group B, member 2 |
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NP_068804.1
257 aa |
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NR0B2, Pan troglodytes
nuclear receptor subfamily 0, group B, member 2 |
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XP_001146990.1
257 aa |
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NR0B2, Canis lupus familiaris
nuclear receptor subfamily 0, group B, member 2 |
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XP_854945.1
279 aa |
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NR0B2, Bos taurus
nuclear receptor subfamily 0, group B, member 2 |
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XP_592675.1
260 aa |
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Nr0b2, Mus musculus
nuclear receptor subfamily 0, group B, member 2 |
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NP_035980.1
260 aa |
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Nr0b2, Rattus norvegicus
nuclear receptor subfamily 0, group B, member 2 |
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NP_476474.1
260 aa |
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NR0B2, Gallus gallus
nuclear receptor subfamily 0, group B, member 2 |
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XP_001231199.1
262 aa |
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nr0b2a, Danio rerio
nuclear receptor subfamily 0, group B, member 2a |
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XP_001921455.1
171 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Obesity, mild, early-onset. |
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Mus musculus |
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Normal phenotype. |
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Liver/biliary system phenotype. |
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Homeostasis/metabolism phenotype. |
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Endocrine/exocrine gland phenotype. |
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Digestive/alimentary phenotype. |
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Reproductive system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Song G & Wang L.Nuclear receptor SHP activates miR-206 expression via a cascade dual inhibitory mechanism. PLoS One 4, e6880(2009). |
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Jung GS, et al.The orphan nuclear receptor SHP attenuates renal fibrosis. J Am Soc Nephrol 20, 2162-70(2009). |
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Song G & Wang L.MiR-433 and miR-127 arise from independent overlapping primary transcripts encoded by the miR-433-127 locus. PLoS One 3, e3574(2008). |
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Enya M, et al.Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients. Hum Mutat 29, E271-7(2008). |
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He N, et al.Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth. Gastroenterology 134, 793-802(2008). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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NR_LBD (cl11397) The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators. |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Nr0b2 includes H.sapiens NR0B2 and R.norvegicus Nr0b2. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Expressed sequence BC058069 |
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Nuclear receptor subfamily 0, group B, member 2 |
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Nuclear receptor subfamily 0, group B, member 2 |
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Small heterodimer partner |
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Nuclear receptor subfamily 0, group B, member 2 |
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Nuclear receptor subfamily 0, group B, member 2 |
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Transcribed locus, moderately similar to XP_592675.1 PREDICTED: similar to N... |
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