Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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ABCA2, Homo sapiens
ATP-binding cassette, sub-family A (ABC1), member 2 |
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NP_001597.2
2436 aa |
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ABCA2, Canis lupus familiaris
ATP-binding cassette, sub-family A (ABC1), member 2 |
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XP_537788.2
2395 aa |
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Abca2, Mus musculus
ATP-binding cassette, sub-family A (ABC1), member 2 |
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NP_031405.2
2433 aa |
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Abca2, Rattus norvegicus
ATP-binding cassette, sub-family A (ABC1), member 2 |
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NP_077372.1
2434 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Nervous system phenotype. |
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Life span-post-weaning/aging. |
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Homeostasis/metabolism phenotype. |
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Hearing/vestibular/ear phenotype. |
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Growth/size phenotype. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Reproductive system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Sakai H, et al.ABCA2 deficiency results in abnormal sphingolipid metabolism in mouse brain. J Biol Chem 282, 19692-9(2007). |
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Saito T, et al.Expression of ABCA2 protein in both non-myelin-forming and myelin-forming Schwann cells in the rodent peripheral nerve. Neurosci Lett 414, 35-40(2007). |
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Mack JT, et al."Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol Cell Biol 27, 44-53(2007). |
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Wollmer MA, et al.Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 141B, 534-6(2006). |
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Broccardo C, et al.ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain. J Neurochem 97, 345-55(2006). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Abca2 includes H.sapiens ABCA2 and R.norvegicus Abca2. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Transcribed locus, strongly similar to NP_001597.2 ATP-binding cassette, sub... |
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Transcribed locus, strongly similar to NP_001597.2 ATP-binding cassette, sub... |
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Transcribed locus, weakly similar to XP_001112698.1 PREDICTED: similar to AT... |
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ATP-binding cassette, sub-family A (ABC1), member 2 |
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Si:dkey-266h7.1 |
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Similar to ATP-binding cassette, sub-family A (ABC1), member 2 |
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ATP-binding cassette, sub-family A (ABC1), member 2 |
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Tumor necrosis factor receptor superfamily, member 25 |
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CDNA clone: FLbaf66d08, mRNA sequence |
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Transcribed locus, moderately similar to NP_077372.1 ATP-binding cassette, s... |
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Similar to ATP-binding cassette, sub-family A, member 2 isoform b |
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ATP-binding cassette, sub-family A (ABC1), member 2 |
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Transcribed locus, moderately similar to XP_692128.2 PREDICTED: similar to A... |
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Transcribed locus, moderately similar to NP_001597.2 ATP-binding cassette, s... |
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Transcribed locus, moderately similar to NP_077372.1 ATP-binding cassette, s... |
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ATP-binding cassette, sub-family A (ABC1), member 2 |
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Transcribed locus, strongly similar to NP_001597.2 ATP-binding cassette, sub... |
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Transcribed locus, strongly similar to NP_001597.2 ATP-binding cassette, sub... |
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Transcribed locus, strongly similar to NP_001597.2 ATP-binding cassette, sub... |
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Transcribed locus, moderately similar to XP_001481309.1 PREDICTED: similar t... |
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Transcribed locus, moderately similar to NP_001597.2 ATP-binding cassette, s... |
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