Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
|
 |
Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
|
|
RXRB, Homo sapiens
retinoid X receptor, beta |
|
|
NP_068811.1
533 aa |
   |
|
|
RXRB, Pan troglodytes
retinoid X receptor, beta |
|
|
XP_001168893.1
533 aa |
|
|
|
RXRB, Canis lupus familiaris
retinoid X receptor, beta |
|
|
XP_862727.1
545 aa |
|
|
|
RXRB, Bos taurus
retinoid X receptor, beta |
|
|
NP_001077109.1
532 aa |
|
|
|
Rxrb, Mus musculus
retinoid X receptor beta |
|
|
NP_035436.1
520 aa |
|
|
|
Rxrb, Rattus norvegicus
retinoid X receptor beta |
|
|
NP_996731.2
518 aa |
|
|
|
rxrba, Danio rerio
retinoid x receptor, beta a |
|
|
NP_571350.1
438 aa |
|
|
|
rxrbb, Danio rerio
retinoid x receptor, beta b |
|
|
NP_571313.1
422 aa |
|
|
|
usp, Drosophila melanogaster
ultraspiracle |
|
|
NP_476781.1
508 aa |
|
|
|
AgaP_AGAP002095, Anopheles gambiae
AGAP002095-PA |
|
|
XP_320944.4
474 aa |
|
|
Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
|
| |
Drosophila melanogaster |
|
Encodes a protein that binds the promoter region of Cp15. Mutants are recessive lethals. usp/usp or usp/γ progeny of usp/+ mothers die during the first larval instar or in the molt to the second instar. Those that die during the molt to the second instar sometimes have incompletely molted the first instar set of larval spiracles and thus have two sets of spiracles (Perrimon, Engstrom and Mahowald, 1985; Oro, McKeown and Evans, 1992). usp/Y embryos derived from usp/usp germ cells die just prior to or just after hatching with an oval scar on the ventral surface of the posterior eighth abdominal or ninth abdominal segment. (See FlyBase for complete description.) |
| |
Mus musculus |
|
Normal phenotype. |
|
Nervous system phenotype. |
|
Liver/biliary system phenotype. |
|
Lethality-prenatal/perinatal. |
|
Homeostasis/metabolism phenotype. |
|
Hearing/vestibular/ear phenotype. |
|
Endocrine/exocrine gland phenotype. |
|
Cellular phenotype. |
|
Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
|
Immune system phenotype. |
|
Reproductive system phenotype. |
|
Skin/coat/nails phenotype. |
|
Hematopoietic system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
|
|
Brtko J, et al.Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation. Mech Ageing Dev 128, 594-600(2007). |
|
Xiao CW, et al.Dietary soy protein isolate modifies hepatic retinoic acid receptor-beta proteins and inhibits their DNA binding activity in rats. J Nutr 137, 1-6(2007). |
|
Wheeler DE & Nijhout HF.A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. Bioessays 25, 994-1001(2003). |
|
Love JD, et al.The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. J Biol Chem 277, 11385-91(2002). |
|
Clayton GM, et al.The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. Proc Natl Acad Sci U S A 98, 1549-54(2001). |
|
|
|
|
Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
|
|
|
|
NR_LBD (cl11397) The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators. |
Related Homology Resources
Links to curated and computed homology information found in other databases.
|
|
Orthology group for M.musculus Rxrb includes H.sapiens RXRB and R.norvegicus Rxrb. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
|
|
Strain Liverpool chromosome 3 |
|
RXR type hormone receptor |
|
Retinoid X receptor, beta |
|
Retinoid X receptor, beta |
|
Ultraspiracle |
|
Similar to retinoid X receptor, beta |
|
Retinoid X receptor, beta |
|
Retinoid X receptor beta |
|
Transcribed locus, strongly similar to XP_862535.1 PREDICTED: similar to ret... |
|
Transcribed locus, moderately similar to NP_571350.1 retinoid x receptor, be... |
|
Retinoid X receptor beta |
|
Retinoid X receptor beta (RXRbeta) mRNA, RXRbeta-BRACA1 allele |
|
|
|
|