Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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RXRA, Homo sapiens
retinoid X receptor, alpha |
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NP_002948.1
462 aa |
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RXRA, Pan troglodytes
retinoid X receptor, alpha |
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XP_520345.2
601 aa |
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RXRA, Canis lupus familiaris
retinoid X receptor, alpha |
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XP_548399.2
435 aa |
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RXRA, Bos taurus
retinoid X receptor, alpha |
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XP_887036.3
404 aa |
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Rxra, Mus musculus
retinoid X receptor alpha |
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NP_035435.1
467 aa |
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Rxra, Rattus norvegicus
retinoid X receptor alpha |
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NP_036937.1
467 aa |
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rxraa, Danio rerio
retinoid X receptor, alpha a |
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XP_001923873.1
458 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Pigmentation phenotype. |
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Normal phenotype. |
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Nervous system phenotype. |
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Renal/urinary system phenotype. |
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Muscle phenotype. |
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Liver/biliary system phenotype. |
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Limbs/digits/tail phenotype. |
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Lethality-postnatal. |
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Lethality-prenatal/perinatal. |
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Homeostasis/metabolism phenotype. |
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Hearing/vestibular/ear phenotype. |
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Growth/size phenotype. |
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Endocrine/exocrine gland phenotype. |
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Embryogenesis phenotype. |
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Digestive/alimentary phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Immune system phenotype. |
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Respiratory system phenotype. |
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Reproductive system phenotype. |
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Skeleton phenotype. |
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Vision/eye phenotype. |
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Skin/coat/nails phenotype. |
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Hematopoietic system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Kourelis K, et al.Retinoid X receptor overexpression desensitizes laryngeal epithelium to carcinogenic effects associated with epidermal growth factor receptor upregulation. J Otolaryngol Head Neck Surg 38, 233-9(2009). |
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Kölsch H, et al.RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism. J Cell Mol Med 13, 589-98(2009). |
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Gyamfi MA & Wan YJ.Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis. J Biol Chem 284, 9321-30(2009). |
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Gyamfi MA, et al.Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice. Toxicol Appl Pharmacol 234, 166-78(2009). |
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Lin YW, et al.9-cis retinoic acid induces retinoid X receptor localized to the mitochondria for mediation of mitochondrial transcription. Biochem Biophys Res Commun 377, 351-4(2008). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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NR_LBD (cl11397) The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators. |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Rxra includes H.sapiens RXRA and R.norvegicus Rxra. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Ultraspiracle protein |
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Retinoid X receptor, alpha |
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Nuclear hormone receptor RXR |
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Retinoid X receptor, alpha |
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Retinoid x receptor, beta b |
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Retinoid x receptor, beta a |
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Retinoid x receptor, alpha b |
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RXRalpha-B |
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Similar to retinoid X receptor alpha |
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Similar to retinoid X receptor-alpha |
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Clone CGX53-A06 mRNA sequence |
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Transcribed locus, strongly similar to XP_687423.1 PREDICTED: similar to ret... |
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Retinoid X receptor, alpha |
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MRNA, clone QnpA-12387: similar to Homo sapiens retinoid X receptor, alpha (... |
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Retinoid X receptor, alpha |
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Transcribed locus, moderately similar to NP_035435.1 retinoid X receptor alp... |
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Retinoid X receptor alpha |
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Retinoid X receptor (rxr gene) |
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Retinoid X receptor beta 2 |
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Retinoid X receptor beta 1 |
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Retinoid X receptor alpha 1 |
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Transcribed locus, strongly similar to NP_996731.2 retinoid X receptor beta ... |
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Retinoid X receptor |
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Transcribed locus, strongly similar to XP_701960.2 PREDICTED: similar to ret... |
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Transcribed locus, strongly similar to NP_571350.1 retinoid x receptor, beta... |
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Transcribed locus, strongly similar to XP_001342978.1 PREDICTED: similar to ... |
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Retinoid X receptor alpha |
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Transcribed locus, strongly similar to NP_035435.1 retinoid X receptor alpha... |
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Transcribed locus, moderately similar to NP_571350.1 retinoid x receptor, be... |
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Retinoic acid receptor RXR |
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Retinoic X receptor-like |
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Hypothetical LOC593382 |
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Retinoid X receptor, alpha |
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Retinoid X receptor, beta |
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Retinoid X receptor beta |
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Retinoid X receptor, beta |
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Retinoid X receptor, alpha |
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