Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Reduced triglycerides, susceptibility to. |
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Mus musculus |
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Life span-post-weaning/aging. |
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Lethality-postnatal. |
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Lethality-prenatal/perinatal. |
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Adipose tissue phenotype. The observable morphological and physiological characteristics of mammalian fat tissue that are manifested through development and lifespan. |
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Homeostasis/metabolism phenotype. |
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Growth/size phenotype. |
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Digestive/alimentary phenotype. |
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Immune system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Kersten S, et al.Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids. Arterioscler Thromb Vasc Biol 29, 969-74(2009). |
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Yin W, et al.Genetic variation in ANGPTL4 provides insights into protein processing and function. J Biol Chem 284, 13213-22(2009). |
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Chomel C, et al.Interaction of the coiled-coil domain with glycosaminoglycans protects angiopoietin-like 4 from proteolysis and regulates its antiangiogenic activity. FASEB J 23, 940-9(2009). |
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Talmud PJ, et al.ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk. Arterioscler Thromb Vasc Biol 28, 2319-25(2008). |
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Folsom AR, et al.Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Metabolism 57, 1591-6(2008). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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FReD (cl00085) Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Angptl4 includes H.sapiens ANGPTL4 and R.norvegicus Angptl4. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Angiopoietin-like 4 |
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Angiopoietin-like 4 |
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Si:rp71-39b20.7 |
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Angiopoietin-like 4 |
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Transcribed locus, weakly similar to XP_692048.2 PREDICTED: hypothetical pro... |
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Transcribed locus, weakly similar to NP_004664.1 angiopoietin-like 1 precurs... |
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Angiopoietin-like 4 |
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Transcribed locus, strongly similar to NP_954546.1 angiopoietin-like 4 [Ratt... |
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Hypothetical protein LOC711693 |
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Angiopoietin-like 4 |
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Transcribed locus, weakly similar to XP_692048.2 PREDICTED: hypothetical pro... |
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Transcribed locus, strongly similar to NP_001039508.1 angiopoietin-like 4 [B... |
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Angiopoietin-like 4 |
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Transcribed locus, moderately similar to XP_692048.2 PREDICTED: hypothetical... |
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Angiopoietin-like 4 |
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Transcribed locus, strongly similar to XP_001232284.1 PREDICTED: similar to ... |
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Transcribed locus, strongly similar to XP_001376351.1 PREDICTED: similar to ... |
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Transcribed locus, moderately similar to XP_001232284.1 PREDICTED: similar t... |
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