Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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ABCA3, Homo sapiens
ATP-binding cassette, sub-family A (ABC1), member 3 |
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NP_001080.2
1704 aa |
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ABCA3, Pan troglodytes
ATP-binding cassette, sub-family A (ABC1), member 3 |
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XP_510744.2
1704 aa |
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ABCA3, Canis lupus familiaris
ATP-binding cassette, sub-family A (ABC1), member 3 |
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XP_537004.2
1758 aa |
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ABCA3, Bos taurus
ATP-binding cassette, sub-family A (ABC1), member 3 |
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XP_001790255.1
1704 aa |
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Abca3, Mus musculus
ATP-binding cassette, sub-family A (ABC1), member 3 |
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NP_001034670.1
1704 aa |
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Abca3, Rattus norvegicus
ATP-binding cassette, sub-family A (ABC1), member 3 |
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XP_220219.4
1708 aa |
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ABCA3, Gallus gallus
ATP-binding cassette, sub-family A (ABC1), member 3 |
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XP_414701.2
1641 aa |
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CG1718, Drosophila melanogaster
CG1718 |
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NP_608445.1
1713 aa |
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AgaP_AGAP012155, Anopheles gambiae
AGAP012155-PA |
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XP_320377.4
1710 aa |
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AgaP_AGAP006380, Anopheles gambiae
AGAP006380-PA |
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XP_001688862.1
1652 aa |
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AgaP_AGAP006379, Anopheles gambiae
AGAP006379-PA |
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XP_557048.3
1643 aa |
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AgaP_AGAP007504, Anopheles gambiae
AGAP007504-PA |
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XP_308371.4
1719 aa |
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AgaP_AGAP012156, Anopheles gambiae
AGAP012156-PA |
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XP_552044.3
1663 aa |
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abt-4, Caenorhabditis elegans
ABC Transporter family |
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NP_503175.1
1802 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Surfactant metabolism dysfunction, pulmonary, 3. |
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Mus musculus |
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Renal/urinary system phenotype. |
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Lethality-prenatal/perinatal. |
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Homeostasis/metabolism phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Respiratory system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Anandarajan M, et al.ABCA3 Deficiency: an unusual cause of respiratory distress in the newborn. Ulster Med J 78, 51-2(2009). |
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Matsumura Y, et al.Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants associated with nonfatal pediatric interstitial lung disease. Am J Physiol Lung Cell Mol Physiol 295, L698-707(2008). |
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Chapuy B, et al.Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration. Leukemia 22, 1576-86(2008). |
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Karjalainen MK, et al.Haplotype analysis of ABCA3: association with respiratory distress in very premature infants. Ann Med 40, 56-65(2008). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Abca3 includes H.sapiens ABCA3 and R.norvegicus Abca3. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Transcribed locus, weakly similar to XP_001377138.1 PREDICTED: similar to AT... |
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Transcribed locus, weakly similar to XP_693353.2 PREDICTED: hypothetical pro... |
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Transcribed locus, weakly similar to XP_001477700.1 PREDICTED: similar to AT... |
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Transcribed locus, moderately similar to XP_320377.4 AGAP012155-PA [Anophele... |
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Transcribed locus, weakly similar to XP_001477700.1 PREDICTED: similar to AT... |
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Strain Liverpool chromosome 2 |
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Strain Liverpool chromosome 2 |
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Strain Liverpool |
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Transcribed locus, moderately similar to XP_001688862.1 AGAP006380-PA [Anoph... |
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Transcribed locus, strongly similar to XP_557048.3 AGAP006379-PA [Anopheles ... |
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Transcribed locus, weakly similar to XP_001477700.1 PREDICTED: similar to AT... |
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Transcribed locus, weakly similar to XP_292468.5 PREDICTED: hypothetical pro... |
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ATP-binding cassette, sub-family A (ABC1), member 3 |
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ABC Transporter family |
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ATP-binding cassette, sub-family A (ABC1), member 3 |
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Hypothetical LOC564344 |
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CG32186 |
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CG31213 |
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CG1718 |
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CG1494 |
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Transcribed locus, moderately similar to NP_608445.1 CG1718 CG1718-PA [Droso... |
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ATP-binding cassette, sub-family A (ABC1), member 3 |
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Similar to ATP-binding cassette, sub-family A member 3 |
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ATP-binding cassette, sub-family A (ABC1), member 3 |
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ATP-binding cassette, sub-family A (ABC1), member 3 |
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Similar to ENSANGP00000009155 |
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ABC transporter family protein |
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Transcribed locus, weakly similar to XP_001477700.1 PREDICTED: similar to AT... |
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Transcribed locus, moderately similar to XP_001367846.1 PREDICTED: similar t... |
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