Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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NR1H2, Homo sapiens
nuclear receptor subfamily 1, group H, member 2 |
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NP_009052.3
461 aa |
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NR1H2, Pan troglodytes
nuclear receptor subfamily 1, group H, member 2 |
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XP_512838.2
512 aa |
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NR1H2, Canis lupus familiaris
nuclear receptor subfamily 1, group H, member 2 |
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XP_851316.1
455 aa |
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NR1H2, Bos taurus
nuclear receptor subfamily 1, group H, member 2 |
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NP_001014883.1
498 aa |
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Nr1h2, Mus musculus
nuclear receptor subfamily 1, group H, member 2 |
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NP_033499.1
446 aa |
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Nr1h2, Rattus norvegicus
nuclear receptor subfamily 1, group H, member 2 |
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NP_113814.1
443 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Normal phenotype. |
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Nervous system phenotype. |
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Homeostasis/metabolism phenotype. |
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Endocrine/exocrine gland phenotype. |
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Cellular phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Reproductive system phenotype. |
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Skin/coat/nails phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Asquith DL, et al.Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis. Arthritis Rheum 60, 2655-65(2009). |
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Stenson BM, et al.Activation of liver X receptor regulates substrate oxidation in white adipocytes. Endocrinology 150, 4104-13(2009). |
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Wu S, et al.Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling. Cardiovasc Res 84, 119-26(2009). |
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Xu J, et al.Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity. J Leukoc Biol 86, 401-9(2009). |
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Hsu JJ, et al.T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. FEBS Lett 583, 1344-8(2009). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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NR_LBD (cl11397) The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators. |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Nr1h2 includes H.sapiens NR1H2 and R.norvegicus Nr1h2. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Nuclear receptor subfamily 1, group H, member 2 |
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Nuclear receptor subfamily 1, group H, member 2 |
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Nuclear receptor subfamily 1, group H, member 2 |
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Brain cDNA clone: QorA-10318, similar to human nuclear receptor subfamily 1,... |
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Brain cDNA clone: QmoA-11219, similar to human nuclear receptor subfamily 1,... |
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Similar to Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orp... |
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Transcribed locus, strongly similar to NP_989873.1 nuclear receptor subfamil... |
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Nuclear receptor subfamily 1, group H, member 2 |
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Transcribed locus, strongly similar to NP_001014883.1 nuclear receptor subfa... |
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Nuclear receptor subfamily 1, group H, member 2 |
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Transcribed locus, strongly similar to NP_009052.3 nuclear receptor subfamil... |
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Nuclear receptor subfamily 1, group H, member 2 |
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MGC81974 protein |
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