Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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NR1H3, Homo sapiens
nuclear receptor subfamily 1, group H, member 3 |
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NP_005684.2
447 aa |
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NR1H3, Pan troglodytes
nuclear receptor subfamily 1, group H, member 3 |
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XP_001168229.1
447 aa |
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NR1H3, Canis lupus familiaris
nuclear receptor subfamily 1, group H, member 3 |
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XP_540745.1
447 aa |
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NR1H3, Bos taurus
nuclear receptor subfamily 1, group H, member 3 |
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NP_001014861.1
447 aa |
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Nr1h3, Mus musculus
nuclear receptor subfamily 1, group H, member 3 |
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NP_038867.2
445 aa |
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Nr1h3, Rattus norvegicus
nuclear receptor subfamily 1, group H, member 3 |
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NP_113815.1
445 aa |
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NR1H3, Gallus gallus
nuclear receptor subfamily 1, group H, member 3 |
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NP_989873.1
409 aa |
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nr1h3, Danio rerio
nuclear receptor subfamily 1, group H, member 3 |
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NP_001017545.1
412 aa |
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EcR, Drosophila melanogaster
Ecdysone receptor |
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NP_724456.1
849 aa |
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AgaP_AGAP012211, Anopheles gambiae
AGAP012211-PA |
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XP_320323.4
477 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Normal phenotype. |
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Nervous system phenotype. |
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Liver/biliary system phenotype. |
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Homeostasis/metabolism phenotype. |
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Cellular phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Mirth CK, et al.The ecdysone receptor controls the post-critical weight switch to nutrition-independent differentiation in Drosophila wing imaginal discs. Development 136, 2345-53(2009). |
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Tricoire H, et al.The steroid hormone receptor EcR finely modulates Drosophila lifespan during adulthood in a sex-specific manner. Mech Ageing Dev 130, 547-52(2009). |
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Azoitei A & Spindler-Barth M.DNA affects ligand binding of the ecdysone receptor of Drosophila melanogaster. Mol Cell Endocrinol 303, 91-9(2009). |
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Dave VP, et al.Functional genomics of blood cellular LXR-alpha gene in human coronary heart disease. J Mol Cell Cardiol 46, 536-44(2009). |
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Romani P, et al.Cell survival and polarity of Drosophila follicle cells require the activity of ecdysone receptor B1 isoform. Genetics 181, 165-75(2009). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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NR_LBD (cl11397) The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators. |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Nr1h3 includes H.sapiens NR1H3 and R.norvegicus Nr1h3. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Strain Liverpool chromosome 2 |
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Transcribed locus, strongly similar to XP_320323.2 ENSANGP00000009112 [Anoph... |
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Ecdyson receptor |
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Ecdysone receptor |
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Nuclear receptor subfamily 1, group H, member 3 |
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Nuclear receptor subfamily 1, group H, member 3 |
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Nuclear receptor subfamily 1, group H, member 3 |
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Hypothetical protein LOC797864 |
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Ecdysone receptor |
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Nuclear receptor subfamily 1, group H, member 3 |
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Nuclear receptor subfamily 1, group H, member 3 |
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Transcribed locus, strongly similar to NP_005684.1 nuclear receptor subfamil... |
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Nuclear receptor subfamily 1, group H, member 3 |
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Nuclear receptor subfamily 1, group H, member 3 |
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Nuclear receptor subfamily 1, group H, member 3 |
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Transcribed locus, strongly similar to NP_001014861.1 nuclear receptor subfa... |
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Transcribed locus, strongly similar to NP_001017545.1 nuclear receptor subfa... |
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Nuclear receptor subfamily 1, group H, member 3 |
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Transcribed locus, strongly similar to NP_005684.1 nuclear receptor subfamil... |
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Nuclear receptor subfamily 1, group H, member 3 |
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Ecdysone receptor |
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