Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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AGT, Homo sapiens
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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NP_000020.1
485 aa |
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AGT, Pan troglodytes
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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NP_001009032.1
485 aa |
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AGT, Canis lupus familiaris
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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XP_536348.2
491 aa |
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AGT, Bos taurus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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XP_001790086.1
476 aa |
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Agt, Mus musculus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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NP_031454.3
482 aa |
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Agt, Rattus norvegicus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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NP_602308.1
477 aa |
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AGT, Gallus gallus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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XP_419584.1
464 aa |
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agt, Danio rerio
angiotensinogen |
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NP_932329.1
454 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Preeclampsia, susceptibility to. |
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Hypertension, essential, susceptibility to. |
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Renal tubular dysgenesis. |
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Mus musculus |
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Nervous system phenotype. |
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Renal/urinary system phenotype. |
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Muscle phenotype. |
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Liver/biliary system phenotype. |
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Lethality-postnatal. |
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Adipose tissue phenotype. The observable morphological and physiological characteristics of mammalian fat tissue that are manifested through development and lifespan. |
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Homeostasis/metabolism phenotype. |
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Growth/size phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Reproductive system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Okada M, et al.Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts. J Clin Pharm Ther 34, 288-99(2009). |
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Henry M, et al.Endogenous angiotensin II facilitates GABAergic neurotransmission afferent to the Na+-responsive neurons of the rat median preoptic nucleus. Am J Physiol Regul Integr Comp Physiol 297, R783-92(2009). |
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Schrier RW.Interactions between angiotensin II and arginine vasopressin in water homeostasis. Kidney Int 76, 137-9(2009). |
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Sarzani R, et al.Angiotensinogen promoter variants influence gene expression in human kidney and visceral adipose tissue. J Hum Hypertens(2009). |
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Gusev K, et al.Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling. Circ Res 105, 42-50(2009). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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SERPIN (cl00137) SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Agt includes H.sapiens AGT and R.norvegicus Agt. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Angiotensinogen |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Clone CFW08-C06 mRNA sequence |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Transcribed locus, strongly similar to NP_000020.1 angiotensinogen prepropro... |
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Brain cDNA clone: QmoA-10278, similar to human angiotensinogen (serine (or c... |
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Angiotensinogen |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Angiotensinogen precursor (agt gene) |
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Transcribed locus, strongly similar to NP_001107554.1 angiotensinogen (serpi... |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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Transcribed locus, moderately similar to NP_001107554.1 angiotensinogen (ser... |
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Transcribed locus, moderately similar to XP_001379210.1 PREDICTED: hypotheti... |
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Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
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