Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Normal phenotype. |
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Muscle phenotype. |
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Lethality-postnatal. |
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Adipose tissue phenotype. The observable morphological and physiological characteristics of mammalian fat tissue that are manifested through development and lifespan. |
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Growth/size phenotype. |
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Digestive/alimentary phenotype. |
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Immune system phenotype. |
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Reproductive system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Rensen SS, et al.Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation 118, 828-36(2008). |
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Rensen SS, et al.Expression of the smoothelin gene is mediated by alternative promoters. Cardiovasc Res 55, 850-63(2002). |
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Bär H, et al.Smoothelin is an indicator of reversible phenotype modulation of smooth muscle cells in balloon-injured rat carotid arteries. Basic Res Cardiol 97, 9-16(2002). |
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Krämer J, et al.Identification and characterization of novel smoothelin isoforms in vascular smooth muscle. J Vasc Res 38, 120-32(2001). |
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Rensen S, et al.Structure and chromosome location of Smtn, the mouse smoothelin gene. Cytogenet Cell Genet 89, 225-9(2000). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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CH (cl00030) Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Smtn includes H.sapiens SMTN and R.norvegicus Smtn. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Smoothelin |
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Smoothelin |
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Smoothelin |
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Smoothelin |
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Similar to smoothelin isoform a |
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Transcribed locus, moderately similar to NP_038898.1 smoothelin [Mus musculu... |
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Smoothelin |
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Similar to smoothelin |
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Transcribed locus, strongly similar to NP_001070347.1 hypothetical protein L... |
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Transcribed locus, strongly similar to NP_599031.1 smoothelin isoform b [Hom... |
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Transcribed locus, moderately similar to XP_001343032.1 PREDICTED: hypotheti... |
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Smoothelin |
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Transcribed locus, strongly similar to NP_599032.1 smoothelin isoform a [Hom... |
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Smoothelin |
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Finished cDNA, clone TEgg008h05 |
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Hypothetical protein MGC68765 |
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Hypothetical protein MGC115008 |
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