Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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RFX3, Homo sapiens
regulatory factor X, 3 (influences HLA class II expression) |
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NP_602304.1
749 aa |
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RFX3, Pan troglodytes
regulatory factor X, 3 (influences HLA class II expression) |
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XP_520464.2
739 aa |
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RFX3, Canis lupus familiaris
regulatory factor X, 3 (influences HLA class II expression) |
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XP_861070.1
757 aa |
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RFX3, Bos taurus
regulatory factor X, 3 (influences HLA class II expression) |
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XP_618263.3
677 aa |
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Rfx3, Mus musculus
regulatory factor X, 3 (influences HLA class II expression) |
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NP_035395.2
749 aa |
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rfx3, Danio rerio
regulatory factor X, 3 (influences HLA class II expression) |
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NP_001073517.1
765 aa |
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Rfx, Drosophila melanogaster
Rfx, isoform A |
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NP_649999.2
897 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Normal phenotype. |
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Lethality-prenatal/perinatal. |
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Growth/size phenotype. |
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Embryogenesis phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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El Zein L, et al.RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies. J Cell Sci 122, 3180-9(2009). |
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Ait-Lounis A, et al.Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas. Diabetes 56, 950-9(2007). |
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Baas D, et al.A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells. Eur J Neurosci 24, 1020-30(2006). |
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Vandaele C, et al.Drosophila regulatory factor X is an embryonic type I sensory neuron marker also expressed in spermatids and in the brain of Drosophila. Mech Dev 103, 159-62(2001). |
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Durand B, et al.Cloning and characterization of dRFX, the Drosophila member of the RFX family of transcription factors. Gene 246, 285-93(2000). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Rfx3 includes H.sapiens RFX3. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Transcribed locus, moderately similar to XP_001116573.1 PREDICTED: similar t... |
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Similar to Rfx CG6312-PA |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Zgc:153245 |
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Rfx |
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Similar to Regulatory factor X, 3 (influences HLA class II expression) |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Transcribed locus, weakly similar to XP_001845597.1 rfx transcription factor... |
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Testis cDNA clone: QtsA-12177, similar to human regulatory factor X, 3 (infl... |
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Similar to regulatory factor X3 isoform b |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Transcribed locus, moderately similar to NP_001073517.1 hypothetical protein... |
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Regulatory factor X, 3 (influences HLA class II expression) |
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Regulatory factor X, 3 (influences HLA class II expression) |
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