1: HomoloGene:4143. Gene conserved in Euarchontoglires Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MKRN3,  Homo sapiens
makorin ring finger protein 3
    NP_005655.1
507 aa
Domain ImageDomain Image
   MKRN3,  Pan troglodytes
makorin ring finger protein 3
    XP_510258.2
507 aa
Domain ImageDomain Image
   Mkrn3,  Mus musculus
makorin, ring finger protein, 3
    NP_035876.2
544 aa
Domain ImageDomain Image
   Mkrn3,  Rattus norvegicus
makorin, ring finger protein, 3
    XP_218735.4
590 aa
Domain ImageDomain Image


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenrate Alignments




PubMed
Articles associated with genes and sequences of this entry plus additional related articles.

 
Jong MT, et al.
Imprinting of a RING zinc-finger encoding gene in the mouse chromosome region homologous to the Prader-Willi syndrome genetic region. Hum Mol Genet 8, 795-803(1999).
 
Jong MT, et al.
A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region. Hum Mol Genet 8, 783-93(1999).
 
Kobayashi S, et al.
Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region. Biochem Biophys Res Commun 290, 403-8(2002).
 
Watanabe T, et al.
Differential chromatin packaging of genomic imprinted regions between expressed and non-expressed alleles. Hum Mol Genet 9, 3029-35(2000).
 
Lee S, et al.
Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype. Hum Mol Genet 9, 1813-9(2000).
 

 


Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.

 
RING (cl09104)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...
 
zf-CCCH (cl11592)
  Zinc finger C-x8-C-x5-C-x3-H type (and similar).



Related Homology Resources
Links to curated and computed homology information found in other databases.

 
Orthology group for M.musculus Mkrn3 includes H.sapiens MKRN3 and R.norvegicus Mkrn3.



UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.

 
Similar to Makorin-3 (Zinc finger protein 127) (RING finger protein 63)
 
Makorin, ring finger protein, 3
 
Makorin, ring finger protein, 3
 
Transcribed locus, strongly similar to NP_001086242.1 MGC84269 protein [Xeno...