Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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OPRM1, Homo sapiens
opioid receptor, mu 1 |
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NP_001008503.2
418 aa |
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OPRM1, Pan troglodytes
opioid receptor, mu 1 |
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NP_001029087.1
401 aa |
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OPRM1, Canis lupus familiaris
opioid receptor, mu 1 |
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XP_541158.2
401 aa |
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OPRM1, Bos taurus
opioid receptor, mu 1 |
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NP_776833.1
401 aa |
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Oprm1, Mus musculus
opioid receptor, mu 1 |
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NP_001034741.1
438 aa |
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Oprm1, Rattus norvegicus
opioid receptor, mu 1 |
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NP_037203.1
398 aa |
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oprm1, Danio rerio
opioid receptor, mu 1 |
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NP_571782.1
384 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Response to morphine-6-glucuronide. |
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Epilepsy, idiopathic generalized, susceptibility to. |
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Mus musculus |
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Normal phenotype. |
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No phenotypic analysis. No description of morphological, physiological or behavioral information presented. |
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Nervous system phenotype. |
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Life span-post-weaning/aging. |
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Homeostasis/metabolism phenotype. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Touch/vibrissae phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Deb I, et al.Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction. J Neurochem(2009). |
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Miranda R, et al.Initial Evidence of an Association Between OPRM1 and Adolescent Alcohol Misuse. Alcohol Clin Exp Res(2009). |
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Fukuda K, et al.[Postoperative pain management following orthognathic surgery in consideration of individual differences--is the antinociceptive effect of fentanyl related to the genotype involving nucleotide at OPRM1?] Masui 58, 1102-8(2009). |
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de Velasco EM, et al.Mu opioid receptor from the zebrafish exhibits functional characteristics as those of mammalian mu opioid receptor. Zebrafish 6, 259-68(2009). |
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Way BM, et al.Variation in the micro-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection. Proc Natl Acad Sci U S A 106, 15079-84(2009). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Oprm1 includes H.sapiens OPRM1 and R.norvegicus Oprm1. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Opioid receptor, mu 1 |
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Hypothetical protein LOC791871 |
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Opioid receptor, mu 1 |
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Similar to opioid receptor B |
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Opioid receptor, mu 1 |
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Mu-opioid receptor |
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Opioid receptor, mu 1 |
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Opioid receptor, mu 1 |
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Opioid receptor, mu 1 |
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Mu opioid receptor |
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