1: HomoloGene:3336. Gene conserved in Coelomata Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NCAM2,  Homo sapiens
neural cell adhesion molecule 2
    NP_004531.2
837 aa
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   NCAM2,  Pan troglodytes
neural cell adhesion molecule 2
    XP_531397.2
837 aa
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   NCAM2,  Canis lupus familiaris
neural cell adhesion molecule 2
    XP_544829.2
881 aa
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   NCAM2,  Bos taurus
neural cell adhesion molecule 2
    XP_615721.4
728 aa
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   Ncam2,  Mus musculus
neural cell adhesion molecule 2
    NP_035084.1
727 aa
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   Ncam2,  Rattus norvegicus
neural cell adhesion molecule 2
    NP_981954.1
837 aa
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   NCAM2,  Gallus gallus
neural cell adhesion molecule 2
    XP_425540.2
852 aa
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   zgc:152904,  Danio rerio
zgc:152904
    NP_001070212.1
809 aa
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   ncam2,  Danio rerio
neural cell adhesion molecule 2
    NP_571905.1
795 aa
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   Fas2,  Drosophila melanogaster
Fasciclin 2
    NP_525066.1
873 aa
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   AgaP_AGAP002802,  Anopheles gambiae
AGAP002802-PA
    XP_312112.3
855 aa
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Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenrate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.


  Mus musculus
 
Normal phenotype.
 
Nervous system phenotype.
 
Taste/olfaction phenotype.



PubMed
Articles associated with genes and sequences of this entry plus additional related articles.

 
Rasmussen KK, et al.
Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping. J Mol Biol 382, 1113-20(2008).
 
Kohsaka H, et al.
In vivo induction of postsynaptic molecular assembly by the cell adhesion molecule Fasciclin2. J Cell Biol 179, 1289-300(2007).
 
Hamlin JA, et al.
Differential expression of the mammalian homologue of fasciclin II during olfactory development in vivo and in vitro. J Comp Neurol 474, 438-52(2004).
 
Alenius M & Bohm S.
Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons. Development 130, 917-27(2003).
 
Sharrow M & Tiemeyer M.
Gliolectin-mediated carbohydrate binding at the Drosophila midline ensures the fidelity of axon pathfinding. Development 128, 4585-95(2001).
 

 


Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.

 
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...
 
IG (cl00093)
  Immunoglobulin domain family; members are components of immunoglobulins, neuroglia, cell surface glycoproteins, such as, T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, such as, butyrophilin and chondroitin sulfate proteoglycan core...



Related Homology Resources
Links to curated and computed homology information found in other databases.

 
Orthology group for M.musculus Ncam2 includes H.sapiens NCAM2 and R.norvegicus Ncam2.



UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.

 
Strain Liverpool
 
Transcribed locus, moderately similar to XP_312112.2 ENSANGP00000016208 [Ano...
 
Similar to Fasciclin 2 CG3665-PB, isoform B
 
Neural cell adhesion molecule 2
 
Neural cell adhesion molecule 2
Zgc:152904
 
Neural cell adhesion molecule 2
 
Fasciclin 2
 
Neural cell adhesion molecule 2
 
Transcribed locus, moderately similar to NP_571905.1 neural cell adhesion mo...
 
Neural cell adhesion molecule 2
 
Brain cDNA clone: QorA-11022, similar to human neural cell adhesion molecule...
 
Similar to neural cell adhesion molecule 2 precursor
 
Neural cell adhesion molecule 2
 
Transcribed locus, strongly similar to NP_001070212.1 hypothetical protein L...
 
Neural cell adhesion molecule 2
 
Transcribed locus, strongly similar to NP_981954.1 neural cell adhesion mole...
 
Neural cell adhesion molecule 2