1: HomoloGene:32448. Gene conserved in Coelomata Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   RBCK1,  Homo sapiens
RanBP-type and C3HC4-type zinc finger containing 1
    NP_112506.2
510 aa
Domain Image
   RBCK1,  Pan troglodytes
RanBP-type and C3HC4-type zinc finger containing 1
    XP_514455.2
510 aa
Domain Image
   RBCK1,  Canis lupus familiaris
RanBP-type and C3HC4-type zinc finger containing 1
    XP_542942.2
634 aa
Domain ImageDomain Image
   RBCK1,  Bos taurus
RanBP-type and C3HC4-type zinc finger containing 1
    NP_001068629.1
510 aa
Domain ImageDomain Image
   Rbck1,  Mus musculus
RanBP-type and C3HC4-type zinc finger containing 1
    NP_001077390.1
508 aa
Domain ImageDomain Image
   Rbck1,  Rattus norvegicus
RanBP-type and C3HC4-type zinc finger containing 1
    NP_068532.1
498 aa
Domain Image
   RBCK1,  Gallus gallus
RanBP-type and C3HC4-type zinc finger containing 1
    XP_427987.2
215 aa
Domain ImageDomain Image
   zgc:91964,  Danio rerio
zgc:91964
    NP_001002168.1
515 aa
Domain Image
   LOC100149751,  Danio rerio
hypothetical protein LOC100149751
    XP_001918435.1
515 aa
Domain Image
   AgaP_AGAP009239,  Anopheles gambiae
AGAP009239-PA
    XP_553178.3
1877 aa
Domain ImageDomain Image


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenrate Alignments




PubMed
Articles associated with genes and sequences of this entry plus additional related articles.

 
Yoshimoto N, et al.
Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1. FEBS J 276, 6375-85(2009).
 
Yoshimoto N, et al.
Cytoplasmic tethering of a RING protein RBCK1 by its splice variant lacking the RING domain. Biochem Biophys Res Commun 335, 550-7(2005).
 
Yamanaka K, et al.
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nat Cell Biol 5, 336-40(2003).
 
Tokunaga C, et al.
Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1. FEBS Lett 435, 11-5(1998).
 
Tokunaga C, et al.
Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins. Biochem Biophys Res Commun 244, 353-9(1998).
 

 


Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.

 
UBQ (cl00155)
  Ubiquitin homologs; Includes ubiquitin and ubiquitin-like proteins. Ubiquitin-mediated proteolysis is part of the regulated turnover of proteins required for controlling cell cycle progression. Other family members are protein modifiers that perform a...
 
RING (cl09104)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...
 
zf-RanBP (cl02656)
  Zn-finger in Ran binding protein and others.



Related Homology Resources
Links to curated and computed homology information found in other databases.

 
Orthology group for M.musculus Rbck1 includes H.sapiens RBCK1 and R.norvegicus Rbck1.



UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.

 
Strain Liverpool
 
Strain Liverpool chromosome 2
Transcribed locus, strongly similar to XP_553178.3 AGAP009239-PA [Anopheles ...
 
RanBP-type and C3HC4-type zinc finger containing 1
 
RanBP-type and C3HC4-type zinc finger containing 1
 
Zgc:91964
 
Zgc:175152
 
Similar to hCG2019817
 
RanBP-type and C3HC4-type zinc finger containing 1
 
RanBP-type and C3HC4-type zinc finger containing 1
 
Transcribed locus, weakly similar to NP_006453.1 RanBP-type and C3HC4-type z...
 
Similar to ubiquitin conjugating enzyme 7 interacting protein 3 isoform 2
 
RanBP-type and C3HC4-type zinc finger containing 1
 
Transcribed locus, strongly similar to NP_006453.1 ubiquitin conjugating enz...
 
Transcribed locus, strongly similar to NP_001068629.1 hypothetical protein L...
 
RanBP-type and C3HC4-type zinc finger containing 1
 
Transcribed locus, moderately similar to NP_001002168.1 hypothetical protein...
 
Transcribed locus, moderately similar to NP_001104670.1 hypothetical protein...
 
Similar to C20orf18
 
Transcribed locus, strongly similar to NP_112506.2 RanBP-type and C3HC4-type...
 
Transcribed locus, strongly similar to NP_006453.1 RanBP-type and C3HC4-type...