Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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SERPINB6, Homo sapiens
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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NP_004559.4
376 aa |
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SERPINB6, Canis lupus familiaris
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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XP_848373.1
381 aa |
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SERPINB6, Bos taurus
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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XP_871118.3
379 aa |
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SERPINB6, Bos taurus
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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NP_777214.1
378 aa |
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LOC782894, Bos taurus
similar to thrombin inhibitor |
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XP_001249947.2
377 aa |
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LOC617396, Bos taurus
similar to thrombin inhibitor |
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XP_874742.2
377 aa |
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Serpinb6a, Mus musculus
serine (or cysteine) peptidase inhibitor, clade B, member 6a |
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NP_033280.1
378 aa |
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Serpinb6a, Rattus norvegicus
serine (or cysteine) peptidase inhibitor, clade B, member 6a |
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NP_954516.1
379 aa |
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SERPINB6, Gallus gallus
serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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NP_001006377.1
379 aa |
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serpinb1l3, Danio rerio
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 |
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NP_956230.1
380 aa |
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zgc:173729, Danio rerio
zgc:173729 |
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NP_001103200.1
439 aa |
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LOC792004, Danio rerio
hypothetical LOC792004 |
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XP_001331039.2
384 aa |
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im:7148243, Danio rerio
im:7148243 |
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XP_697505.3
440 aa |
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serpinb1l4, Danio rerio
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 |
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NP_956235.1
393 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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No phenotypic analysis. No description of morphological, physiological or behavioral information presented. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Scott FL, et al.SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes. J Biochem 142, 435-42(2007). |
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Scarff KL, et al.Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke. Mol Cell Biol 24, 4075-82(2004). |
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Strik MC, et al.Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers. Blood 103, 2710-7(2004). |
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Scarff KL, et al.A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice. Genesis 36, 149-57(2003). |
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Kishi T, et al.Distribution of serine proteinase inhibitor, clade B, member 6 (Serpinb6) in the adult mouse brain. Brain Res Gene Expr Patterns 1, 175-80(2002). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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SERPIN (cl00137) SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Serpinb6a includes H.sapiens SERPINB6 and R.norvegicus Serpinb6a. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Similar to thrombin inhibitor |
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Similar to thrombin inhibitor |
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Serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 |
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Hypothetical protein LOC792004 |
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Zgc:173729 |
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Im:7148243 |
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Transcribed locus, weakly similar to NP_001009892.1 serpin peptidase inhibit... |
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Serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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Transcribed locus, weakly similar to NP_001079786.1 hypothetical protein LOC... |
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Clone CNB79-B06 mRNA sequence |
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Transcribed locus, weakly similar to XP_687783.1 PREDICTED: similar to serin... |
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Similar to Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiprotein... |
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Leukocyte elastase inhibitor |
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Transcribed locus, weakly similar to NP_001009892.1 serpin peptidase inhibit... |
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Transcribed locus, moderately similar to NP_001009892.1 serpin peptidase inh... |
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Transcribed locus, weakly similar to NP_001117987.1 leukocyte elastase inhib... |
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Transcribed locus, weakly similar to NP_109591.1 serine (or cysteine) protei... |
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Transcribed locus, moderately similar to XP_697505.2 PREDICTED: similar to s... |
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Transcribed locus, moderately similar to NP_956230.1 serpin peptidase inhibi... |
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Transcribed locus, moderately similar to NP_001103200.1 hypothetical protein... |
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Transcribed locus, moderately similar to NP_001006377.1 serine (or cysteine)... |
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Serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
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Hypothetical protein LOC100135333 |
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Hypothetical protein MGC64421 |
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