Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Multiple myeloma. |
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Mus musculus |
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Tumorigenesis. Induction of new growth. |
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Immune system phenotype. |
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Hematopoietic system phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Do TN, et al.An intronic polymorphism of IRF4 gene influences gene transcription in vitro and shows a risk association with childhood acute lymphoblastic leukemia in males. Biochim Biophys Acta(2009). |
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Mudter J, et al.IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation. Arch Immunol Ther Exp (Warsz) 57, 369-76(2009). |
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Gathany AH, et al.Relationship between interferon regulatory factor 4 genetic polymorphisms, measures of sun sensitivity and risk for non-Hodgkin lymphoma. Cancer Causes Control(2009). |
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Gualco G, et al.Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma. Hum Pathol 40, 565-71(2009). |
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Feldman AL, et al.Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas. Leukemia 23, 574-80(2009). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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IRF (cl00096) Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Irf4 includes H.sapiens IRF4 and R.norvegicus Irf4. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Interferon regulatory factor 4 |
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Novel protein similar to vertebrate interferon regulatory factor 4 (IRF4) |
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Interferon regulatory factor 4 |
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Interferon regulatory factor 4 |
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Interferon regulatory factor 4 |
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Transcribed locus, moderately similar to NP_001087097.1 interferon consensus... |
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Transcribed locus, strongly similar to XP_870405.2 PREDICTED: similar to Int... |
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Transcribed locus, moderately similar to XP_698990.2 PREDICTED: hypothetical... |
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Interferon regulatory factor 4 |
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Transcribed locus, moderately similar to XP_001341945.1 PREDICTED: similar t... |
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