PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Nakamura Y, et al.Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularis. J Clin Endocrinol Metab 94, 2192-8(2009). |
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Birtwistle J, et al.The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis. Mutat Res 662, 67-74(2009). |
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Choi JH, et al.Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice. J Reprod Dev 54, 408-12(2008). |
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Svensson PA, et al.Regulation of human aldoketoreductase 1C3 (AKR1C3) gene expression in the adipose tissue. Cell Mol Biol Lett 13, 599-613(2008). |
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Azzarello J, et al.Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system. J Histochem Cytochem 56, 853-61(2008). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Aldo_ket_red (cl00470) Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and... |
Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Akr1c18 includes H.sapiens AKR1C3 and R.norvegicus Akr1c18. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Similar to Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid d... |
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Similar to Prostaglandin-F synthase 1 (PGF synthase 1) (PGF 1) (Prostaglandi... |
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Aldo-keto reductase family 1 member C3 -like |
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Similar to prostaglandin F synthetase II |
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Similar to prostaglandin F synthase-like1 protein |
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Similar to AKR1C1 protein |
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Aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydr... |
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Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenas... |
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Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenas... |
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Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenas... |
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Aldo-keto reductase family 1, member C1 |
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Prostaglandin F synthase |
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Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenas... |
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Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alp... |
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Aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydr... |
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Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile a... |
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Aldo-keto reductase family 1 member C1 |
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Aldo-keto reductase family 1 member C3 |
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Dd-4 mRNA for 3(20)alpha-hydroxysteroid/dihydrodiol dehydrogenase |
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Transcribed locus, moderately similar to NP_001809.2 aldo-keto reductase fam... |
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Aldo-keto reductase family 1, member C1 |
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Similar to Aldo-keto reductase family 1 member C4 (Chlordecone reductase) (C... |
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Hypothetical protein LOC722480 |
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Aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydr... |
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Aldo-keto reductase family 1, member C3 |
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Aldo-keto reductase family 1, member C1 |
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Aldo-keto reductase family 1, member C21 |
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Aldo-keto reductase family 1, member C18 |
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Aldo-keto reductase family 1, member C6 |
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RIKEN cDNA 4921521F21 gene |
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20-alpha-hydroxysteroid dehydrogenase |
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Transcribed locus, moderately similar to NP_003730.4 aldo-keto reductase fam... |
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Prostaglandin F synthase |
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Transcribed locus, strongly similar to NP_851370.1 aldo-keto reductase famil... |
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Transcribed locus, strongly similar to NP_001033673.1 hypothetical protein L... |
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Transcribed locus, strongly similar to XP_001250815.1 PREDICTED: similar to ... |
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Transcribed locus, moderately similar to XP_871063.2 PREDICTED: similar to A... |
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Aldo-keto reductase family 1, member C18 |
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Similar to 20-alpha-hydroxysteroid dehydrogenase |
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Aldo-keto reductase family 1, member C6 |
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Aldo-keto reductase family 1, member C21 |
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Putative aldo-keto reductase family 1 member C1 |
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Putative aldo-keto reductase family 1 member C2 |
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Transcribed locus, strongly similar to NP_001038035.1 putative aldo-keto red... |
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Hypothetical LOC496490 |
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Transcribed locus, strongly similar to NP_001087353.1 MGC85548 protein [Xeno... |
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Hypothetical protein LOC594893 |
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MGC85548 protein |
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Hypothetical protein LOC100049750 |
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