1: HomoloGene:10198. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PAG1,  Homo sapiens
phosphoprotein associated with glycosphingolipid microdomains 1
    NP_060910.3
432 aa
   PAG1,  Pan troglodytes
phosphoprotein associated with glycosphingolipid microdomains 1
    XP_001168080.1
432 aa
   PAG1,  Canis lupus familiaris
phosphoprotein associated with glycosphingolipid microdomains 1
    XP_853555.1
433 aa
   PAG1,  Bos taurus
phosphoprotein associated with glycosphingolipid microdomains 1
    XP_871074.1
434 aa
   Pag1,  Mus musculus
phosphoprotein associated with glycosphingolipid microdomains 1
    NP_444412.2
429 aa
   PAG1,  Gallus gallus
phosphoprotein associated with glycosphingolipid microdomains 1
    XP_418306.2
318 aa
   LOC100003365,  Danio rerio
similar to phosphoprotein associated with glycosphingolipid microdomains 1
    XP_001339529.1
405 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenrate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.


  Mus musculus
 
Immune system phenotype.
 
Hematopoietic system phenotype.



PubMed
Articles associated with genes and sequences of this entry plus additional related articles.

 
Feng X, et al.
Overexpression of Csk-binding protein contributes to renal cell carcinogenesis. Oncogene 28, 3320-31(2009).
 
Inomata M, et al.
Impairment in a negative regulatory system for TCR signaling in CD4+ T cells from old mice. FEBS Lett 581, 3039-43(2007).
 
Smida M, et al.
A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation. Blood 110, 596-615(2007).
 
Takeuchi S.
Expression and purification of human PAG, a transmembrane adapter protein using an insect cell expression system and its structure basis. Protein J 25, 295-9(2006).
 
Dobenecker MW, et al.
The ubiquitously expressed Csk adaptor protein Cbp is dispensable for embryogenesis and T-cell development and function. Mol Cell Biol 25, 10533-42(2005).
 

 



Related Homology Resources
Links to curated and computed homology information found in other databases.

 
Orthology group for M.musculus Pag1 includes H.sapiens PAG1.



UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.

 
Phosphoprotein associated with glycosphingolipid microdomains 1
 
Hypothetical protein LOC100003365
 
Phosphoprotein associated with glycosphingolipid microdomains 1
 
Phosphoprotein associated with glycosphingolipid microdomains 1
 
Similar to phosphoprotein associated with glycosphingolipid microdomains 1
 
Phosphoprotein associated with glycosphingolipid microdomains 1
Transcribed locus, moderately similar to XP_001339529.1 PREDICTED: hypotheti...
 
Csk binding protein
 
Finished cDNA, clone TGas030a24
 
MGC80192 protein