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hybB hydrogenase 2 membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948615, updated on 4-Apr-2024

Summary

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Gene symbol
hybB
Gene description
hydrogenase 2 membrane subunit
Primary source
ASAP:ABE-0009830
Locus tag
b2995
See related
ECOCYC:EG11800
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2989
Summary
The HybB protein is predicted to be an integral membrane component of hydrogenase 2 . [More information is available at EcoCyc: EG11800].
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Genomic context

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Sequence:
NC_000913.3 (3142986..3144164, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase maturation protein HybF Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 maturation protease Neighboring gene hydrogenase 2 large subunit Neighboring gene hydrogenase 2 iron-sulfur protein Neighboring gene hydrogenase 2 small subunit Neighboring gene DUF2623 domain-containing protein YghW

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amino acid variants of the HybB membrane subunit of Escherichia coli [NiFe]-hydrogenase-2 support a role in proton transfer. Lubek D, et al. FEBS Lett, 2019 Aug. PMID 31260099
  2. Physiology and bioenergetics of [NiFe]-hydrogenase 2-catalyzed H2-consuming and H2-producing reactions in Escherichia coli. Pinske C, et al. J Bacteriol, 2015 Jan. PMID 25368299, Free PMC Article
  3. Isolation and characterisation of a soluble active fragment of hydrogenase isoenzyme 2 from the membranes of anaerobically grown Escherichia coli. Ballantine SP, et al. Eur J Biochem, 1986 Apr 15. PMID 3516690
  4. Maturation of [NiFe]-hydrogenases in Escherichia coli. Forzi L, et al. Biometals, 2007 Jun. PMID 17216401
  5. The hydrogenases and formate dehydrogenases of Escherichia coli. Sawers G. Antonie Van Leeuwenhoek, 1994. PMID 7747941

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anaerobic electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in anaerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in anaerobic respiration IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
hydrogenase 2 membrane subunit
NP_417469.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3142986..3144164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417469.1 hydrogenase 2 membrane subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417469.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6C9QE14, A0A7D7EY88, A0A8T5ZFM9
    Conserved Domains (1) summary
    PRK10881
    Location:1 → 392
    PRK10881; Ni/Fe-hydrogenase cytochrome b subunit
Nucleotide Protein
Heading Accession and Version

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