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speC constitutive ornithine decarboxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947457, updated on 4-Apr-2024

Summary

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Gene symbol
speC
Gene description
constitutive ornithine decarboxylase
Primary source
ASAP:ABE-0009730
Locus tag
b2965
See related
ECOCYC:EG10961
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2960
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Genomic context

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Sequence:
NC_000913.3 (3107020..3109155, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene membrane-bound lytic murein transglycosylase C Neighboring gene nucleoside:H(+) symporter NupG Neighboring gene protein YqgH Neighboring gene DUF554 domain-containing protein YqgA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Primary structure of the speC gene encoding biosynthetic ornithine decarboxylase in Escherichia coli. Boyle SM, et al. Gene, 1994 Dec 30. PMID 7828866
  2. Biosynthetic and biodegradative ornithine and arginine decarboxylases from Escherichia coli. Morris DR, et al. Methods Enzymol, 1983. PMID 6353148
  3. Ornithine decarboxylase from Escherichia coli: stimulation of the enzyme activity by nucleotides. Hölttä E, et al. Biochem Biophys Res Commun, 1972 Jun 9. PMID 4555250
  4. The regulation of polyamine synthesis during the stringent control in Escherichia coli. Hölttä E, et al. Biochem Biophys Res Commun, 1974 Aug 5. PMID 4370496
  5. Non-competitive inhibition of ornithine decarboxylase by a phosphopeptide and phosphoamino acids. Tsirka SA, et al. Biochim Biophys Acta, 1986 Dec 10. PMID 3096379

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables guanosine tetraphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables ornithine decarboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ornithine decarboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ornithine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in putrescine biosynthetic process from ornithine IEA
Inferred from Electronic Annotation
more info
  
involved_in spermidine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spermidine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
constitutive ornithine decarboxylase
NP_417440.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3107020..3109155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417440.4 constitutive ornithine decarboxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417440.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AA88EMQ6
    Conserved Domains (1) summary
    PRK13578
    Location:1 → 711
    PRK13578; ornithine decarboxylase; Provisional
Nucleotide Protein
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