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folP bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase [ Chlamydia trachomatis D/UW-3/CX ]

Gene ID: 884393, updated on 22-Nov-2017

Summary

Gene symbol
folP
Gene description
bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase
Locus tag
CT_613
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Chlamydia trachomatis D/UW-3/CX (strain: D/UW-3/CX)
Lineage
Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia/Chlamydophila group; Chlamydia
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Genomic context

Sequence:
NC_000117.1 (692297..693649, complement)

NC_000117.1Genomic Context describing neighboring genes Neighboring gene RNA polymerase sigma-54 factor Neighboring gene virulence protein CADD Neighboring gene gamma-glutamyl ligase Neighboring gene dihydrofolate reductase Neighboring gene dihydroneopterin aldolase Neighboring gene RNA polymerase sigma factor Neighboring gene hypothetical protein

Pathways from PubChem

General protein information

Names
bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000117.1 Reference assembly

    Range
    692297..693649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_220130.1 bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase [Chlamydia trachomatis D/UW-3/CX]

    See identical proteins and their annotated locations for NP_220130.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O84619
    Conserved Domains (2) summary
    COG0801
    Location:4146
    FolK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme transport and metabolism]
    cd00739
    Location:180438
    DHPS; DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and ...