U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

VMA16 H(+)-transporting V0 sector ATPase subunit c'' [ Saccharomyces cerevisiae S288C ]

Gene ID: 856421, updated on 13-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
VMA16
Gene description
H(+)-transporting V0 sector ATPase subunit c''
Primary source
SGD:S000001068
Locus tag
YHR026W
See related
AllianceGenome:SGD:S000001068
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PPA1
Summary
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in vacuolar acidification. Is integral component of membrane. Orthologous to human ATP6V0B (ATPase H+ transporting V0 subunit b). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (160844..161485)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene mitochondrial-processing protease subunit alpha Neighboring gene homoserine kinase Neighboring gene proteasome regulatory particle base subunit RPN1 Neighboring gene dipeptidyl aminopeptidase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Yeast inorganic pyrophosphatase. A model for active-site structure based on 113Cd2+ and 31P NMR studies. Welsh KM, et al. Biochemistry, 1984 Oct 9. PMID 6149765
  2. A yeast protein, homologous to the proteolipid of the chromaffin granule proton-ATPase, is important for cell growth. Apperson M, et al. Biochem Biophys Res Commun, 1990 Apr 30. PMID 2139779
  3. Assembly of the yeast vacuolar H+-ATPase and ATP hydrolysis occurs in the absence of subunit c''. Whyteside G, et al. FEBS Lett, 2005 Jun 6. PMID 15907326
  4. The first putative transmembrane segment of subunit c" (Vma16p) of the yeast V-ATPase is not necessary for function. Nishi T, et al. J Biol Chem, 2003 Feb 21. PMID 12482875
  5. SNARE-mediated membrane fusion arrests at pore expansion to regulate the volume of an organelle. D'Agostino M, et al. EMBO J, 2018 Oct 1. PMID 30120144, Free PMC Article

See all (73) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
enables proton-transporting ATPase activity, rotational mechanism TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vacuolar acidification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
part_of vacuolar proton-transporting V-type ATPase, V0 domain TAS
Traceable Author Statement
more info
 PubMed 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
H(+)-transporting V0 sector ATPase subunit c''
NP_011891.1
  • Subunit c'' of the vacuolar ATPase; v-ATPase functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    160844..161485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179156.1 → NP_011891.1  TPA: H(+)-transporting V0 sector ATPase subunit c'' [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011891.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKX3, P23968
    UniProtKB/TrEMBL
    A0A6A5PX59, A6ZST2, B3LSE7, C7GTV4, C8ZA94, G2WF97, N1P387
    Conserved Domains (2) summary
    cd18177
    Location:59 → 121
    ATP-synt_Vo_c_ATP6F_rpt1; V-type proton ATPase 21 kDa proteolipid subunit (ATP6F/ATP6V0B) and similar proteins
    cd18178
    Location:141 → 192
    ATP-synt_Vo_c_ATP6F_rpt2; V-type proton ATPase 21 kDa proteolipid subunit (ATP6F/ATP6V0B) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
5TJ5_B.1
5VOX_R.1
5VOY_R.1
5VOZ_R.1
6C6L_C.1
6PE4_G.1
6PE5_G.1
P23968.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous