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YAP7 Yap7p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854129, updated on 13-Apr-2024

Summary

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Gene symbol
YAP7
Gene description
Yap7p
Primary source
SGD:S000005388
Locus tag
YOL028C
See related
AllianceGenome:SGD:S000005388
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (270633..271370, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene 1,3-beta-glucanosyltransferase Neighboring gene uncharacterized protein Neighboring gene ribosome-binding protein MDM38 Neighboring gene Mim1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis. Fordyce PM, et al. Nat Biotechnol, 2010 Sep. PMID 20802496, Free PMC Article
  2. Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication. Merhej J, et al. Mol Microbiol, 2015 Jun. PMID 25732006
  3. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Fernandes L, et al. Mol Cell Biol, 1997 Dec. PMID 9372930, Free PMC Article
  4. The mitochondrial iron exporter genes MMT1 and MMT2 in yeast are transcriptionally regulated by Aft1 and Yap1. Li L, et al. J Biol Chem, 2020 Feb 7. PMID 31896574, Free PMC Article
  5. A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Aucher W, et al. Mol Cell Proteomics, 2010 Dec. PMID 20733106, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IC
Inferred by Curator
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Yap7p
NP_014614.1
  • Transcriptional repressor of nitric oxide oxidase; basic leucine zipper (bZIP) transcription factor; neighboring gene, YOL029C, created by frame-shift at position 708, corresponds to C-terminal part of YAP7 orthologs in other species; YAP7 has a paralog, YAP5, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    270633..271370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183282.1 → NP_014614.1  TPA: Yap7p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014614.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W237, Q08182
    UniProtKB/TrEMBL
    A0A8H4F752, B3LJ29, B5VRM3, N1NVP8
    Conserved Domains (2) summary
    cd14688
    Location:126 → 188
    bZIP_YAP; Basic leucine zipper (bZIP) domain of Yeast Activator Protein (YAP) and similar proteins: a DNA-binding and dimerization domain
    pfam10297
    Location:50 → 66
    Hap4_Hap_bind; Minimal binding motif of Hap4 for binding to Hap2/3/5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08182.1

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