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SQE6 squalene monooxygenase 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832482, updated on 15-Oct-2023

Summary

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Gene symbol
SQE6
Gene description
squalene monooxygenase 6
Primary source
Araport:AT5G24160
Locus tag
AT5G24160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
K12G2.4; K12G2_4; squalene monoxygenase 6
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Genomic context

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See SQE6 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Sequence:
Chromosome: 5; NC_003076.8 (8182917..8186704, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FAD/NAD(P)-binding oxidoreductase family protein Neighboring gene FAD/NAD(P)-binding oxidoreductase family protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene Got1/Sft2-like vescicle transport protein family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An example of intron junctional sliding in the gene families encoding squalene monooxygenase homologues in Arabidopsis thaliana and Brassica napus. Schäfer UA, et al. Plant Mol Biol, 1999 Mar. PMID 10350086
  2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_001343845.1
NM_001343846.1
NM_122321.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables squalene monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sterol biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
squalene monooxygenase 6
NP_197804.1
  • squalene monoxygenase 6 (SQE6); FUNCTIONS IN: squalene monooxygenase activity, oxidoreductase activity, FAD binding; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Squalene epoxidase (InterPro:IPR013698), FAD dependent oxidoreductase (InterPro:IPR006076); BEST Arabidopsis thaliana protein match is: FAD/NAD(P)-binding oxidoreductase family protein (TAIR:AT5G24150.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    8182917..8186704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122321.5 → NP_197804.1  squalene monooxygenase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197804.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65402
    UniProtKB/TrEMBL
    A0A178UL03
    Conserved Domains (3) summary
    PLN02985
    Location:3 → 517
    PLN02985; squalene monooxygenase
    pfam13450
    Location:50 → 77
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
    cl21454
    Location:199 → 473
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. NM_001343845.1 → NP_001330191.1  squalene monooxygenase 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA09

  3. NM_001343846.1 → NP_001330190.1  squalene monooxygenase 6 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA10, A0A5S9Y938, A0A654G466
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O65402.1

Gene LinkOut

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