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DGK7 diacylglycerol kinase 7 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829157, updated on 6-Oct-2023

Summary

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Gene symbol
DGK7
Gene description
diacylglycerol kinase 7
Primary source
Araport:AT4G30340
Locus tag
AT4G30340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATDGK7; diacylglycerol kinase 7; F17I23.320; F17I23_320
Summary
encodes a diacylglycerol kinase. Applying a specific diacylglycerol kinase inhibitor to the growth media resulted in reduced root elongation and plant growth. Gene is expressed throughout the plant but is strongest in flowers and young seedlings.
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Genomic context

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Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (14838172..14841147, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein Neighboring gene cyclic nucleotide-gated channel 17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development. Gómez-Merino FC, et al. J Biol Chem, 2005 Oct 14. PMID 16081412
  2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. molecular cloning and characterization of AtDGK7; phosphorylates diacylglycerol molecular species that are typically found in plants; expression is strongest in flowers and young seedlings
    Title: Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001342006.1
NM_119180.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within leaf development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
diacylglycerol kinase 7
NP_567845.4
  • diacylglycerol kinase 7 (DGK7); FUNCTIONS IN: diacylglycerol kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, root development, leaf development; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206), Diacylglycerol kinase, accessory domain (InterPro:IPR000756), Diacylglycerol kinase, plant (InterPro:IPR016961); BEST Arabidopsis thaliana protein match is: diacylglycerol kinase 3 (TAIR:AT2G18730.1); Has 1643 Blast hits to 1452 proteins in 227 species: Archae - 0; Bacteria - 189; Metazoa - 1007; Fungi - 0; Plants - 281; Viruses - 0; Other Eukaryotes - 166 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14838172..14841147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119180.6 → NP_567845.4  diacylglycerol kinase 7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567845.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B0KYU1, F4JQ95, Q9C5L2, Q9M0C6
    UniProtKB/TrEMBL
    A0A178UUX1, A0A5S9XXL3, A0A7G2F795
    Conserved Domains (2) summary
    pfam00609
    Location:287 → 464
    DAGK_acc; Diacylglycerol kinase accessory domain
    pfam00781
    Location:94 → 234
    DAGK_cat; Diacylglycerol kinase catalytic domain

  2. NM_001342006.1 → NP_001328552.1  diacylglycerol kinase 7 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B509
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4JQ95.1

Gene LinkOut

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