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rnd3a Rho family GTPase 3a [ Danio rerio (zebrafish) ]

Gene ID: 80963, updated on 27-Mar-2024

Summary

Official Symbol
rnd3aprovided by ZNC
Official Full Name
Rho family GTPase 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-010319-40
See related
Ensembl:ENSDARG00000076799 AllianceGenome:ZFIN:ZDB-GENE-010319-40
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
arhe; rho8; rnd3; fc39h07; zgc:73080; id:ibd2712; id:ibd2919; wu:fc39h07
Summary
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Is expressed in several structures, including anterior neural keel; mesoderm; musculature system; nervous system; and neural plate. Orthologous to human RND3 (Rho family GTPase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 22
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (12431617..12447113)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (12406840..12422336)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene R3H domain containing 1 Neighboring gene microRNA 128-1 Neighboring gene uncharacterized LOC103909565 Neighboring gene metabolism of cobalamin associated Da Neighboring gene centrosomal protein 70 Neighboring gene adenosine deaminase RNA specific B1a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Rho family GTPase 3a
Names
ras homolog gene family, member E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199522.1NP_955816.1  Rho family GTPase 3a

    See identical proteins and their annotated locations for NP_955816.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059452
    UniProtKB/TrEMBL
    A0A8M1P9I9, Q6PC71
    Related
    ENSDARP00000102340.3, ENSDART00000108609.4
    Conserved Domains (1) summary
    cd04172
    Location:19197
    Rnd3_RhoE_Rho8; Rnd3/RhoE/Rho8 GTPases

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    12431617..12447113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)