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Gpbp1l1 GC-rich promoter binding protein 1-like 1 [ Mus musculus (house mouse) ]

Gene ID: 77110, updated on 16-Apr-2024

Summary

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Official Symbol
Gpbp1l1provided by MGI
Official Full Name
GC-rich promoter binding protein 1-like 1provided by MGI
Primary source
MGI:MGI:1924360
See related
Ensembl:ENSMUSG00000034042 AllianceGenome:MGI:1924360
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5330440M15Rik
Summary
Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human GPBP1L1 (GC-rich promoter binding protein 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 15.8), thymus adult (RPKM 14.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 D1; 4 53.22 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116414357..116451099)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116557179..116593902)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116180277-116180386 Neighboring gene IAP promoted placental gene Neighboring gene STARR-seq mESC enhancer starr_11140 Neighboring gene transmembrane protein 69 Neighboring gene RIKEN cDNA C530005A16 gene Neighboring gene coiled-coil domain containing 17 Neighboring gene nuclear autoantigenic sperm protein (histone-binding) Neighboring gene STARR-positive B cell enhancer ABC_E4648 Neighboring gene STARR-positive B cell enhancer ABC_E4649 Neighboring gene STARR-positive B cell enhancer ABC_E7980

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. USP10 deubiquitinates Tau, mediating its aggregation. Wei Z, et al. Cell Death Dis, 2022 Aug 20. PMID 35987808, Free PMC Article
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC8183

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vasculin-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368177.1 → NP_001355106.1  vasculin-like protein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK077148, AL669953, BC066034
    Consensus CDS
    CCDS18511.1
    UniProtKB/Swiss-Prot
    Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
    Related
    ENSMUSP00000102083.2, ENSMUST00000106475.2
    Conserved Domains (1) summary
    pfam15337
    Location:379 → 449
    Vasculin; Vascular protein family Vasculin-like 1

  2. NM_029868.4 → NP_084144.2  vasculin-like protein 1

    See identical proteins and their annotated locations for NP_084144.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL669953
    Consensus CDS
    CCDS18511.1
    UniProtKB/Swiss-Prot
    Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
    Related
    ENSMUSP00000030460.9, ENSMUST00000030460.15
    Conserved Domains (1) summary
    pfam15337
    Location:379 → 449
    Vasculin; Vascular protein family Vasculin-like 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116414357..116451099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320452.3 → XP_017175941.1  vasculin-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
    Conserved Domains (1) summary
    pfam15337
    Location:379 → 449
    Vasculin; Vascular protein family Vasculin-like 1

  2. XM_006503485.5 → XP_006503548.1  vasculin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006503548.1

    UniProtKB/Swiss-Prot
    Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
    Conserved Domains (1) summary
    pfam15337
    Location:379 → 449
    Vasculin; Vascular protein family Vasculin-like 1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NZP2.1 GenPept UniProtKB/Swiss-Prot:Q6NZP2

Gene LinkOut

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