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RBBP4 RB binding protein 4, chromatin remodeling factor [ Bos taurus (cattle) ]

Gene ID: 767940, updated on 5-Mar-2024

Summary

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Official Symbol
RBBP4provided by VGNC
Official Full Name
RB binding protein 4, chromatin remodeling factorprovided by VGNC
Primary source
VGNC:VGNC:33770
See related
BGD:BT20876; Ensembl:ENSBTAG00000005904
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (120969738..120986312, complement)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101907639 Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene syncoilin, intermediate filament protein Neighboring gene zinc finger and BTB domain containing 8 opposite strand Neighboring gene zinc finger and BTB domain containing 8A Neighboring gene large ribosomal subunit protein uL29-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Taunton J, et al. Science, 1996 Apr 19. PMID 8602529
  2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC128413

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of ESC/E(Z) complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-binding protein RBBP4
Names
RBBP-4
nucleosome-remodeling factor subunit RBAP48
retinoblastoma binding protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077013.2 → NP_001070481.1  histone-binding protein RBBP4

    See identical proteins and their annotated locations for NP_001070481.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105195
    UniProtKB/Swiss-Prot
    A5D9B1, Q3MHL3
    Conserved Domains (3) summary
    sd00039
    Location:128 → 175
    7WD40; WD40 repeat [structural motif]
    pfam12265
    Location:19 → 88
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    cl29593
    Location:122 → 403
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    120969738..120986312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024978303.2 → XP_024834071.1  histone-binding protein RBBP4 isoform X1

    Related
    ENSBTAP00000007758.6, ENSBTAT00000007758.7
    Conserved Domains (3) summary
    sd00039
    Location:127 → 174
    7WD40; WD40 repeat [structural motif]
    pfam12265
    Location:18 → 87
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    cl29593
    Location:121 → 402
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3MHL3.3 GenPept UniProtKB/Swiss-Prot:Q3MHL3

Gene LinkOut

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