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luc7l3 LUC7-like 3 pre-mRNA splicing factor [ Danio rerio (zebrafish) ]

Gene ID: 724014, updated on 27-Mar-2024

Summary

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Official Symbol
luc7l3provided by ZNC
Official Full Name
LUC7-like 3 pre-mRNA splicing factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060616-375
See related
Ensembl:ENSDARG00000014366 AllianceGenome:ZFIN:ZDB-GENE-060616-375
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:136380; zgc:158165
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site selection. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to human LUC7L3 (LUC7 like 3 pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See luc7l3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (58805790..58823763, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (58746483..58764456, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108182857 Neighboring gene Ras association and DIL domains 2a Neighboring gene Ig kappa chain V region 3381-like Neighboring gene Ig lambda chain C region-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Zimmerman MW, et al. Cancer Discov, 2018 Mar. PMID 29284669, Free PMC Article
  2. Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin. Gistelinck C, et al. Sci Rep, 2016 Feb 15. PMID 26876635, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC158165, MGC162864

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mRNA splice site recognition IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U1 snRNP IEA
Inferred from Electronic Annotation
more info
  
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
luc7-like protein 3
Names
cisplatin resistance-associated overexpressed protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045319.1 → NP_001038784.1  luc7-like protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001038784.1

    Status: PROVISIONAL

    Source sequence(s)
    BC117592
    UniProtKB/TrEMBL
    Q1ED13
    Conserved Domains (2) summary
    COG5200
    Location:4 → 244
    LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
    pfam03194
    Location:4 → 244
    LUC7; LUC7 N_terminus

  2. NM_001080591.1 → NP_001074060.1  luc7-like protein 3 isoform 1

    See identical proteins and their annotated locations for NP_001074060.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129146
    UniProtKB/TrEMBL
    A1L1N4
    Related
    ENSDARP00000092027.3, ENSDART00000101253.6
    Conserved Domains (2) summary
    COG5200
    Location:4 → 244
    LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
    pfam03194
    Location:4 → 244
    LUC7; LUC7 N_terminus

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    58805790..58823763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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