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AP2A1 adaptor related protein complex 2 subunit alpha 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 719038, updated on 5-Mar-2024

Summary

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Official Symbol
AP2A1provided by VGNC
Official Full Name
adaptor related protein complex 2 subunit alpha 1provided by VGNC
Primary source
VGNC:VGNC:69962
See related
Ensembl:ENSMMUG00000011612
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
34
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (49750430..49798442)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (45195046..45242243)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene carnitine palmitoyltransferase 1C Neighboring gene uncharacterized LOC106994823 Neighboring gene testis specific serine kinase substrate Neighboring gene fuzzy planar cell polarity protein Neighboring gene mediator complex subunit 25 Neighboring gene PTOV1 extended AT-hook containing adaptor protein Neighboring gene polynucleotide kinase 3'-phosphatase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables clathrin adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in clathrin-dependent endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of AP-2 adaptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of membrane coat IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
AP-2 complex subunit alpha-1
Names
adaptor related protein complex 2 alpha 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266208.2 → NP_001253137.1  AP-2 complex subunit alpha-1

    See identical proteins and their annotated locations for NP_001253137.1

    Status: PROVISIONAL

    Source sequence(s)
    JV046300
    UniProtKB/TrEMBL
    I0FPJ3, I0FPJ5
    Related
    ENSMMUP00000044364.2, ENSMMUT00000065373.2
    Conserved Domains (4) summary
    smart00809
    Location:733 → 836
    Alpha_adaptinC2; Adaptin C-terminal domain
    pfam01602
    Location:29 → 591
    Adaptin_N; Adaptin N terminal region
    pfam02296
    Location:842 → 950
    Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
    sd00044
    Location:332 → 355
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    49750430..49798442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015124408.2 → XP_014979894.2  AP-2 complex subunit alpha-1 isoform X1

    UniProtKB/TrEMBL
    F6PL38
    Related
    ENSMMUP00000015242.4, ENSMMUT00000016269.4
    Conserved Domains (4) summary
    smart00809
    Location:755 → 857
    Alpha_adaptinC2; Adaptin C-terminal domain
    sd00044
    Location:332 → 355
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:29 → 591
    Adaptin_N; Adaptin N terminal region
    pfam02296
    Location:863 → 971
    Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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