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EIF2B3 eukaryotic translation initiation factor 2B subunit gamma [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705862, updated on 5-Mar-2024

Summary

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Official Symbol
EIF2B3provided by VGNC
Official Full Name
eukaryotic translation initiation factor 2B subunit gammaprovided by VGNC
Primary source
VGNC:VGNC:72184
Locus tag
EGK_00691
See related
Ensembl:ENSMMUG00000005342
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (179430370..179576343)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (44416077..44563005, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene HECT domain E3 ubiquitin protein ligase 3 Neighboring gene 28S ribosomal protein S17, mitochondrial Neighboring gene E3 ubiquitin-protein ligase CCNB1IP1 pseudogene Neighboring gene patched 2 Neighboring gene U5 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytoplasmic translational initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of eukaryotic translation initiation factor 2B complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of guanyl-nucleotide exchange factor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translation initiation factor eIF2B subunit gamma; translation initiation factor eIF-2B subunit gamma
Names
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260654.1 → NP_001247583.1  translation initiation factor eIF2B subunit gamma

    See identical proteins and their annotated locations for NP_001247583.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048601
    UniProtKB/TrEMBL
    A0A8J8YKP3, F7GGU0, F7GGU5, G7MGP0
    Related
    ENSMMUP00000072131.1, ENSMMUT00000110235.1
    Conserved Domains (2) summary
    cd04198
    Location:3 → 212
    eIF-2B_gamma_N; The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2
    COG1208
    Location:4 → 447
    GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    179430370..179576343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015138005.2 → XP_014993491.1  translation initiation factor eIF-2B subunit gamma isoform X1

    UniProtKB/TrEMBL
    A0A5F8AH96, F7GGU5
    Related
    ENSMMUP00000077225.1, ENSMMUT00000105286.1
    Conserved Domains (3) summary
    cd04652
    Location:327 → 407
    LbH_eIF2B_gamma_C; eIF-2B gamma subunit, C-terminal Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...
    cd04198
    Location:3 → 189
    eIF-2B_gamma_N; The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2
    COG1208
    Location:4 → 417
    GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]

  2. XM_028843036.1 → XP_028698869.1  translation initiation factor eIF-2B subunit gamma isoform X2

    UniProtKB/TrEMBL
    F7GGU5
    Conserved Domains (2) summary
    cd04652
    Location:289 → 369
    LbH_eIF2B_gamma_C; eIF-2B gamma subunit, C-terminal Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...
    cl11394
    Location:2 → 144
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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