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SUV39H2 SUV39H2 histone lysine methyltransferase [ Sus scrofa (pig) ]

Gene ID: 664651, updated on 5-Mar-2024

Summary

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Official Symbol
SUV39H2provided by VGNC
Official Full Name
SUV39H2 histone lysine methyltransferaseprovided by VGNC
Primary source
VGNC:VGNC:95841
See related
Ensembl:ENSSSCG00000011048
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 6.2), spleen (RPKM 2.9) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 10 NC_010452.4 (46874606..46900058, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 10 NC_010452.3 (51595641..51633086, complement)

Chromosome 10 - NC_010452.4Genomic Context describing neighboring genes Neighboring gene meiosis/spermiogenesis associated 1 Neighboring gene DNA cross-link repair 1C Neighboring gene heat shock protein family A (Hsp70) member 14 Neighboring gene cerebral dopamine neurotrophic factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Downregulation of histone methyltransferase genes SUV39H1 and SUV39H2 increases telomere length in embryonic stem-like cells and embryonic fibroblasts in pigs. Dang-Nguyen TQ, et al. J Reprod Dev, 2013. PMID 23018532, Free PMC Article
  2. Comparative mapping of human chromosome 10 to pig chromosomes 10 and 14. Nonneman D, et al. Anim Genet, 2004 Aug. PMID 15265077

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Knockdown of SUV39H1 and SUV39H2 in embryonic stem-like cells and embryonic fibroblasts increases telomere length.
    Title: Downregulation of histone methyltransferase genes SUV39H1 and SUV39H2 increases telomere length in embryonic stem-like cells and embryonic fibroblasts in pigs.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase SUV39H2
Names
suppressor of variegation 3-9 homolog 2
NP_001034836.1
XP_005668170.1
XP_005668176.1
XP_013835690.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039747.1 → NP_001034836.1  histone-lysine N-methyltransferase SUV39H2

    See identical proteins and their annotated locations for NP_001034836.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ400534
    UniProtKB/TrEMBL
    A0A8D0JMG2, A0A8D0WCK3, C3RZ96, F1RW84, Q27I49
    Related
    ENSSSCP00000055161.1, ENSSSCT00000049142.2
    Conserved Domains (3) summary
    smart00317
    Location:190 → 313
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam00385
    Location:2 → 33
    Chromo; Chromo (CHRromatin Organization MOdifier) domain
    pfam05033
    Location:94 → 182
    Pre-SET; Pre-SET motif

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010452.4 Reference Sscrofa11.1 Primary Assembly

    Range
    46874606..46900058 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005668113.3 → XP_005668170.1  histone-lysine N-methyltransferase SUV39H2 isoform X1

    UniProtKB/TrEMBL
    A0A287A6I1, A0A8D0JMG2, A0A8D0NXY6, C3RZ96
    Related
    ENSSSCP00000039480.1, ENSSSCT00000059014.3
    Conserved Domains (3) summary
    smart00317
    Location:250 → 373
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam00385
    Location:48 → 93
    Chromo; Chromo (CHRromatin Organization MOdifier) domain
    pfam05033
    Location:154 → 242
    Pre-SET; Pre-SET motif

  2. XM_005668119.3 → XP_005668176.1  histone-lysine N-methyltransferase SUV39H2 isoform X2

    See identical proteins and their annotated locations for XP_005668176.1

    UniProtKB/TrEMBL
    A0A8D0JMG2, A0A8D0WCK3, C3RZ96, F1RW84, Q27I49
    Conserved Domains (3) summary
    smart00317
    Location:190 → 313
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam00385
    Location:2 → 33
    Chromo; Chromo (CHRromatin Organization MOdifier) domain
    pfam05033
    Location:94 → 182
    Pre-SET; Pre-SET motif

  3. XM_013980236.2 → XP_013835690.1  histone-lysine N-methyltransferase SUV39H2 isoform X2

    UniProtKB/TrEMBL
    A0A8D0JMG2, A0A8D0WCK3, C3RZ96, F1RW84, Q27I49
    Conserved Domains (3) summary
    smart00317
    Location:190 → 313
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam00385
    Location:2 → 33
    Chromo; Chromo (CHRromatin Organization MOdifier) domain
    pfam05033
    Location:94 → 182
    Pre-SET; Pre-SET motif
Nucleotide Protein Strain
Heading Accession and Version

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