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Scamp4 secretory carrier membrane protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 65170, updated on 11-Apr-2024

Summary

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Official Symbol
Scamp4provided by RGD
Official Full Name
secretory carrier membrane protein 4provided by RGD
Primary source
RGD:68354
See related
Ensembl:ENSRNOG00000018271 AllianceGenome:RGD:68354
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein transport. Located in transport vesicle. Orthologous to human SCAMP4 (secretory carrier membrane protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 82.7), Kidney (RPKM 64.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
7q11
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9752193..9764614, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9101504..9113929, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11969720..11982141, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene BTB domain containing 2 Neighboring gene casein kinase 1, gamma 2 Neighboring gene large ribosomal subunit protein eL31-like Neighboring gene adenosine deaminase, tRNA-specific 3 Neighboring gene abhydrolase domain containing 17A, depalmitoylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Expression of the SCAMP-4 gene, a new member of the secretory carrier membrane protein family, is repressed by progesterone in brain regions associated with female sexual behavior. Krebs CJ, et al. Brain Res Mol Brain Res, 2001 Mar 31. PMID 11295240
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in reproductive behavior NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in recycling endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
secretory carrier-associated membrane protein 4
Names
SCAMP-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031725.2 → NP_113913.2  secretory carrier-associated membrane protein 4

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/Swiss-Prot
    Q9ET20
    UniProtKB/TrEMBL
    A6K8I7, A6K8I8, Q5EAN5
    Related
    ENSRNOP00000024980.4, ENSRNOT00000024980.7
    Conserved Domains (1) summary
    pfam04144
    Location:5 → 179
    SCAMP; SCAMP family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9752193..9764614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006240999.3 → XP_006241061.1  secretory carrier-associated membrane protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006241061.1

    UniProtKB/Swiss-Prot
    Q9ET20
    UniProtKB/TrEMBL
    A6K8I7, A6K8I8, Q5EAN5
    Conserved Domains (1) summary
    pfam04144
    Location:5 → 179
    SCAMP; SCAMP family

  2. XM_017595101.3 → XP_017450590.1  secretory carrier-associated membrane protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q9ET20
    UniProtKB/TrEMBL
    A6K8I7, A6K8I8, Q5EAN5
    Conserved Domains (1) summary
    pfam04144
    Location:5 → 179
    SCAMP; SCAMP family

  3. XM_063264221.1 → XP_063120291.1  secretory carrier-associated membrane protein 4 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ET20.1 GenPept UniProtKB/Swiss-Prot:Q9ET20

Gene LinkOut

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