Gene description

GMP synthase

Locus Tag

APP7_0637

Gene type

protein coding

RefSeq status

Reviewed

Organism

Actinobacillus pleuropneumoniae serovar 7 str. AP76

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus

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Names

GMP synthase

YP_001968431.1

EC 6.3.5.2

contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. YP_001968431.1 GMP synthase (glutamine-hydrolyzing) [Actinobacillus pleuropneumoniae serovar 7 str. AP76]

   UniProtKB/Swiss-Prot

   B3H120

   Conserved Domains (3) summary

   cd01742
   Location:9 – 196
   Blast Score: 678

   GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase. GMP synthetase is a glutamine amidotransferase from the de novo purine biosynthetic pathway. Glutamine amidotransferase (GATase) activity catalyse the transfer of ammonia from...

   cd01997
   Location:228 – 522
   Blast Score: 1280

   GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...

   PRK00074
   Location:3 – 523
   Blast Score: 2784

   guaA; GMP synthase; Reviewed